Detecting high-order epistasis in nonlinear genotype-phenotype maps ZR Sailer, MJ Harms Genetics 205 (3), 1079-1088, 2017 | 141 | 2017 |
High-order epistasis shapes evolutionary trajectories ZR Sailer, MJ Harms PLoS computational biology 13 (5), e1005541, 2017 | 122 | 2017 |
Molecular ensembles make evolution unpredictable ZR Sailer, MJ Harms Proceedings of the National Academy of Sciences 114 (45), 11938-11943, 2017 | 82 | 2017 |
Inferring a complete genotype-phenotype map from a small number of measured phenotypes ZR Sailer, SH Shafik, RL Summers, A Joule, A Patterson-Robert, ... PLoS computational biology 16 (9), e1008243, 2020 | 14 | 2020 |
Topiary: Pruning the manual labor from ancestral sequence reconstruction KN Orlandi, SR Phillips, ZR Sailer, JL Harman, MJ Harms Protein Science 32 (2), e4551, 2023 | 13 | 2023 |
Comparative analysis and ancestral sequence reconstruction of bacterial sortase family proteins generates functional ancestral mutants with different sequence specificities JD Valgardson, SA Struyvenberg, ZR Sailer, IM Piper, JE Svendsen, ... Bacteria 1 (2), 121-135, 2022 | 9 | 2022 |
Uninterpretable interactions: epistasis as uncertainty ZR Sailer, MJ Harms BioRxiv, 378489, 2018 | 9 | 2018 |
Exploring the evolutionary history of kinetic stability in the α-Lytic protease family CF Nixon, SA Lim, ZR Sailer, IN Zheludev, CL Gee, BA Kelch, MJ Harms, ... Biochemistry 60 (3), 170-181, 2021 | 8 | 2021 |
Reproducing machine learning research on binder J Forde, M Bussonnier, FA Fortin, B Granger, T Head, C Holdgraf, ... | 8 | 2018 |
IPython: components for interactive and parallel computing across disciplines. F Perez, M Bussonnier, JD Frederic, BM Froehle, BE Granger, P Ivanov, ... AGU Fall Meeting Abstracts 2013, H51R-02, 2013 | 2 | 2013 |
Using Ancestral Proteins to Probe the Thermodynamic and Kinetic Properties of the Alpha-Lytic Protease Family C Nixon, SA Lim, Z Sailer, M Harms, S Marqusee Biophysical Journal 114 (3), 580a, 2018 | 1 | 2018 |
Molecular Ensembles Shape Evolutionary Trajectories MJ Harms, ZR Sailer, LC Wheeler Biophysical Journal 114 (3), 12a, 2018 | | 2018 |
Predicting Phenotypes in Sparsely Sampled Genotype-Phenotype Maps ZR Sailer University of Oregon, 2018 | | 2018 |
Detecting high-order epistasis in nonlinear ZR Sailer, MJ Harms | | 2017 |