Maria Secrier
Maria Secrier
Lecturer in Computational Biology, UCL Genetics Institute, University College London
Verified email at
Cited by
Cited by
Using graph theory to analyze biological networks
GA Pavlopoulos, M Secrier, CN Moschopoulos, TG Soldatos, S Kossida, ...
BioData mining 4, 1-27, 2011
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis
JMJ Weaver, CS Ross-Innes, N Shannon, AG Lynch, T Forshew, ...
Nature genetics 46 (8), 837-843, 2014
Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance
M Secrier, X Li, N De Silva, MD Eldridge, G Contino, J Bornschein, ...
Nature genetics 48 (10), 1131-1141, 2016
Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics
X Li, HE Francies, M Secrier, J Perner, A Miremadi, N Galeano-Dalmau, ...
Nature communications 9 (1), 2983, 2018
TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A
AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, ...
Nature 603 (7899), 131-137, 2022
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia
M Prudencio, J Humphrey, S Pickles, AL Brown, SE Hill, JM Kachergus, ...
The Journal of clinical investigation 130 (11), 2020
Multicentre cohort study to define and validate pathological assessment of response to neoadjuvant therapy in oesophagogastric adenocarcinoma
F Noble, MA Lloyd, R Turkington, E Griffiths, M O'Donovan, JR O'Neill, ...
Journal of British Surgery 104 (13), 1816-1828, 2017
Identification of prognostic phenotypes of esophageal adenocarcinoma in 2 independent cohorts
T Sawas, S Killcoyne, PG Iyer, KK Wang, TC Smyrk, JB Kisiel, Y Qin, ...
Gastroenterology 155 (6), 1720-1728. e4, 2018
Molecular landscape of esophageal cancer: implications for early detection and personalized therapy
FR Talukdar, M di Pietro, M Secrier, M Moehler, K Goepfert, SSC Lima, ...
Annals of the New York Academy of Sciences 1434 (1), 342-359, 2018
Identification of subtypes of Barrett’s esophagus and esophageal adenocarcinoma based on DNA methylation profiles and integration of transcriptome and genome data
SG Jammula, AC Katz-Summercorn, X Li, C Linossi, E Smyth, S Killcoyne, ...
Gastroenterology 158 (6), 1682-1697. e1, 2020
Visualizing time-related data in biology, a review
M Secrier, R Schneider
Briefings in bioinformatics 15 (5), 771-782, 2014
The ABC of reverse engineering biological signalling systems
M Secrier, T Toni, MPH Stumpf
Molecular BioSystems 5 (12), 1925-1935, 2009
Genomic evidence supports a clonal diaspora model for metastases of esophageal adenocarcinoma
A Noorani, X Li, M Goddard, J Crawte, LB Alexandrov, M Secrier, ...
Nature genetics 52 (1), 74-83, 2020
Arena3D: visualizing time-driven phenotypic differences in biological systems
M Secrier, GA Pavlopoulos, J Aerts, R Schneider
BMC bioinformatics 13, 1-11, 2012
Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium. Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with …
M Secrier, X Li, N de Silva, MD Eldridge, G Contino, J Bornschein, ...
Nat Genet 48 (10), 1131-1141, 2016
Molecular effects of Lapatinib in the treatment of HER2 overexpressing oesophago-gastric adenocarcinoma
N De Silva, L Schulz, A Paterson, W Qain, M Secrier, E Godfrey, H Cheow, ...
British journal of cancer 113 (9), 1305-1312, 2015
A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre-and post-chemotherapy
A Noorani, J Bornschein, AG Lynch, M Secrier, A Achilleos, M Eldridge, ...
Genome research 27 (6), 902-912, 2017
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1
E Garcia, A Hayden, C Birts, E Britton, A Cowie, K Pickard, M Mellone, ...
Scientific reports 6 (1), 32417, 2016
Cell environment shapes TDP-43 function with implications in neuronal and muscle disease
U Šušnjar, N Škrabar, AL Brown, Y Abbassi, H Phatnani, A Cortese, ...
Communications biology 5 (1), 314, 2022
Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization
AL Brown, OG Wilkins, MJ Keuss, SE Hill, M Zanovello, WC Lee, FCY Lee, ...
Biorxiv, 2021.04. 02.438170, 2021
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