Steven M. Cramer

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Shekhar GardeRensselaer Polytechnic InstituteVerified email at rpi.edu
Melissa HolsteinBristol-Myers SquibbVerified email at bms.com
Kaushal RegeFulton Faculty Impact Professor, Chemical Engineering; Chair, Biological Design Graduate ProgramVerified email at asu.edu
Curt BrenemanDean of Science, Professor of Chemistry & Chemical Biology, Rensselaer Polytechnic InstituteVerified email at rpi.edu
Guhan JayaramanProfessor of Biotechnology, IIT Madras ChennaiVerified email at iitm.ac.in
Ying Hourensselaer polytechnic instituteVerified email at merck.com
Deepak NagrathDepartment of Biomedical Engineering, University of MichiganVerified email at umich.edu
Abhinav ShuklaChief Technical Officer, Shattuck LabsVerified email at shattucklabs.com
Todd PrzybycienRensselaer Polytechnic InstituteVerified email at rpi.edu
N. SukumarAmrita Vishwa VidyapeethamVerified email at cb.amrita.edu
Pankaj KarandeAssociate Professor of Chemical and Biological Engineering, Rensselaer Polytechnic InstituteVerified email at rpi.edu
Jonathan DordickRensselaer Polytechnic InstituteVerified email at rpi.edu
Kristin P. BennettProfessor of Mathematical Sciences, Renssealer Polytechnic InstituteVerified email at rpi.edu
Camille BilodeauAssistant ProfessorVerified email at virginia.edu
Hanne Sophie KarkovMSc. Biotechnology Engineering, Rensselaer Polytechnic Institute and Novo Nordisk A/SVerified email at novonordisk.com
J. Christopher LoveProfessor of Chemical Engineering, MITVerified email at mit.edu
Laura CrowellSunflower Therapeutics, PBCVerified email at sunflowertx.com
Minghu SongUniversity of ConnecticutVerified email at uconn.edu
Siddharth ParimalGraduate Student, Rensselaer Polytechnic InstituteVerified email at rpi.edu
Wilfred ChenGore Professor of Chemical Engineering, University of DelawareVerified email at udel.edu

Steven M. Cramer

Institute Professor, Rensselaer Polytechnic Institute

Verified email at rpi.edu - Homepage

chromatography separations downstream bioprocessing protein separations modeling


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Steric mass‐action ion exchange: Displacement profiles and induced salt gradients CA Brooks, SM Cramer AIChE Journal 38 (12), 1969-1978, 1992	632	1992
Prediction of protein retention times in anion-exchange chromatography systems using support vector regression M Song, CM Breneman, J Bi, N Sukumar, KP Bennett, S Cramer, N Tugcu Journal of chemical information and computer sciences 42 (6), 1347-1357, 2002	222	2002
Salting-in and salting-out of hydrophobic solutes in aqueous salt solutions A Kalra, N Tugcu, SM Cramer, S Garde The Journal of Physical Chemistry B 105 (27), 6380-6386, 2001	215	2001
Antibody variable region interactions with Protein A: implications for the development of generic purification processes S Ghose, M Allen, B Hubbard, C Brooks, SM Cramer Biotechnology and bioengineering 92 (6), 665-673, 2005	191	2005
Evaluation and comparison of alternatives to Protein A chromatography: Mimetic and hydrophobic charge induction chromatographic stationary phases S Ghose, B Hubbard, SM Cramer Journal of Chromatography A 1122 (1-2), 144-152, 2006	182	2006
Binding capacity differences for antibodies and Fc‐fusion proteins on protein A chromatographic materials S Ghose, B Hubbard, SM Cramer Biotechnology and bioengineering 96 (4), 768-779, 2007	175	2007
Downstream bioprocessing: recent advances and future promise SM Cramer, MA Holstein Current Opinion in Chemical Engineering 1 (1), 27-37, 2011	167	2011
A holistic approach to protein secondary structure characterization using amide I band Raman spectroscopy SU Sane, SM Cramer, TM Przybycien Analytical biochemistry 269 (2), 255-272, 1999	162	1999
Optimization of preparative ion-exchange chromatography of proteins: linear gradient separations SR Gallant, S Vunnum, SM Cramer Journal of chromatography A 725 (2), 295-314, 1996	156	1996
Membrane chromatographic systems for high-throughput protein separations JA Gerstner, R Hamilton, SM Cramer Journal of Chromatography A 596 (2), 173-180, 1992	145	1992
Characterization of non-linear adsorption properties of dextran-based polyelectrolyte displacers in ion-exchange systems SD Gadam, G Jayaraman, SM Cramer Journal of Chromatography A 630 (1-2), 37-52, 1993	125	1993
Ion-exchange displacement chromatography of proteins Dendritic polymers as novel displacers G Jayaraman, YF Li, JA Moore, SM Cramer Journal of Chromatography A 702 (1-2), 143-155, 1995	118	1995
Prediction of protein retention in ion-exchange systems using molecular descriptors obtained from crystal structure CB Mazza, N Sukumar, CM Breneman, SM Cramer Analytical chemistry 73 (22), 5457-5461, 2001	113	2001
On-demand manufacturing of clinical-quality biopharmaceuticals LE Crowell, AE Lu, KR Love, A Stockdale, SM Timmick, D Wu, Y Wang, ... Nature biotechnology 36 (10), 988-995, 2018	109	2018
A priori prediction of adsorption isotherm parameters and chromatographic behavior in ion-exchange systems A Ladiwala, K Rege, CM Breneman, SM Cramer Proceedings of the National Academy of Sciences 102 (33), 11710-11715, 2005	109	2005
Protein interactions in hydrophobic charge induction chromatography (HCIC) S Ghose, B Hubbard, SM Cramer Biotechnology Progress 21 (2), 498-508, 2005	108	2005
Ion-exchange displacement chromatography of proteins: Dextran-based polyelectrolytes as high affinity displacerss G Jayaraman, SD Gadam, SM Cramer Journal of Chromatography A 630 (1-2), 53-68, 1993	107	1993
Modeling non-linear elution of proteins in ion-exchange chromatography SR Gallant, A Kundu, SM Cramer Journal of Chromatography A 702 (1-2), 125-142, 1995	98	1995
Evaluation of protein adsorption and preferred binding regions in multimodal chromatography using NMR WK Chung, AS Freed, MA Holstein, SA McCallum, SM Cramer Proceedings of the National Academy of Sciences 107 (39), 16811-16816, 2010	96	2010
Investigation of protein retention and selectivity in HIC systems using quantitative structure retention relationship models A Ladiwala, F Xia, Q Luo, CM Breneman, SM Cramer Biotechnology and bioengineering 93 (5), 836-850, 2006	95	2006

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