| Inter-domain tagging implicates caveolin-1 in insulin receptor trafficking and Erk signaling bias in pancreatic beta-cells T Boothe, GE Lim, H Cen, S Skovsø, M Piske, SN Li, IR Nabi, P Gilon, ... Molecular metabolism 5 (5), 366-378, 2016 | 50 | 2016 |
| Reducing insulin via conditional partial gene ablation in adults reverses diet-induced weight gain MM Page, S Skovsø, H Cen, AP Chiu, DA Dionne, DF Hutchinson, GE Lim, ... The FASEB Journal 32 (3), 1196, 2018 | 47 | 2018 |
| Cardiac ryanodine receptor (Ryr2)-mediated calcium signals specifically promote glucose oxidation via pyruvate dehydrogenase MJ Bround, R Wambolt, H Cen, P Asghari, RF Albu, J Han, D McAfee, ... Journal of Biological Chemistry 291 (45), 23490-23505, 2016 | 29 | 2016 |
| Beta-cell specific Insr deletion promotes insulin hypersecretion and improves glucose tolerance prior to global insulin resistance S Skovsø, E Panzhinskiy, J Kolic, HH Cen, DA Dionne, XQ Dai, ... Nature communications 13 (1), 735, 2022 | 28 | 2022 |
| Differential effects of voclosporin and tacrolimus on insulin secretion from human islets J Kolic, L Beet, P Overby, HH Cen, E Panzhinskiy, DR Ure, JL Cross, ... Endocrinology 161 (11), bqaa162, 2020 | 23 | 2020 |
| Human and mouse muscle transcriptomic analyses identify insulin receptor mRNA downregulation in hyperinsulinemia‐associated insulin resistance HH Cen, B Hussein, JD Botezelli, S Wang, JA Zhang, N Noursadeghi, ... The FASEB Journal 36 (1), 2022 | 22 | 2022 |
| 77-Ins2 Gene Bursting Activity Defines a Mature β-Cell State H Modi, J Chu, S Skovsø, C Ellis, NAJ Krentz, Y Zhao, HH Cen, ... Canadian Journal of Diabetes 44 (7), S31, 2020 | 10 | 2020 |
| Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation AMY Zhang, YH Xia, JSH Lin, KH Chu, WCK Wang, TJJ Ruiter, JCC Yang, ... Cell Metabolism 35 (12), 2119-2135. e5, 2023 | 8 | 2023 |
| Transcriptomics for clinical and experimental biology research: hang on a seq T Stokes, HH Cen, P Kapranov, IJ Gallagher, AA Pitsillides, CH Volmar, ... Advanced Genetics 4 (2), 2200024, 2023 | 7 | 2023 |
| Flow‐induced secretion of endothelial heparanase regulates cardiac lipoprotein lipase and changes following diabetes CS Lee, Y Zhai, R Shang, T Wong, AJ Mattison, HH Cen, JD Johnson, ... Journal of the American Heart Association 11 (23), e027958, 2022 | 6 | 2022 |
| Dynamic Ins2 Gene Activity Defines β-Cell Maturity States CMJ Chu, H Modi, C Ellis, NAJ Krentz, S Skovsø, YB Zhao, H Cen, ... Diabetes 71 (12), 2612-2631, 2022 | 6 | 2022 |
| Eukaryotic translation initiation factor 2A protects pancreatic beta cells during endoplasmic reticulum stress while rescuing translation inhibition E Panzhinskiy, S Skovsø, HH Cen, KY Chu, K MacDonald, ... bioRxiv, 2021.02. 17.431676, 2021 | 6 | 2021 |
| Modulation of Insr and insulin receptor signaling by hyperinsulinemia in vitro and in vivo H Cen, JD Botezelli, JD Johnson Biorxiv, 2021 | 4 | 2021 |
| Proteomic predictors of individualized nutrient-specific insulin secretion in health and disease J Kolic, WQG Sun, HH Cen, J Ewald, JC Rogalski, S Sasaki, H Sun, ... medRxiv, 2023.05. 24.23290298, 2023 | 2 | 2023 |
| Hyperinsulinemia acts through acinar cell insulin receptors to drive obesity-associated pancreatic cancer initiation by promoting digestive enzyme production and inflammation AMY Zhang, YH Xia, JSH Lin, KH Chu, TJJ Ruiter, JCC Yang, N Chen, ... bioRxiv, 2022.05. 06.490845, 2022 | 2 | 2022 |
| Transcriptomic analysis of human and mouse muscle during hyperinsulinemia demonstrates insulin receptor downregulation as a mechanism for insulin resistance HH Cen, JD Botezelli, S Wang, N Noursadeghi, N Jessen, JA Timmons, ... bioRxiv, 556571, 2019 | 2 | 2019 |
| Insulin-dependent and-independent dynamics of insulin receptor trafficking in muscle cells HH Cen, J Rogalski, L Abraham, MR Gold, LJ Foster, JD Johnson bioRxiv, 2021.06. 29.450241, 2021 | 1 | 2021 |
| Imaging Ins2 gene activity and single-cell RNA sequencing reveal heterogeneous beta cell states H Modi, H Cen, S Skovso, X Hu, N Krentz, D Dionne, S Xuan, M Huising, ... DIABETOLOGIA 61, S17-S17, 2018 | 1 | 2018 |
| Abstract B055: Hyperinsulinemia acts via acinar cell insulin receptors to drive obesity-associated pancreatic cancer initiation AMY Zhang, YH Xia, JSH Lin, KH Chu, WCK Wang, TJJ Ruiter, JCC Yang, ... Cancer Research 84 (2_Supplement), B055-B055, 2024 | | 2024 |
| Hyperinsulinemia acts via acinar cell insulin receptors to drive obesityassociated pancreatic cancer initiation AMY Zhang, YH Xia, JSH Lin, KH Chu, WCK Wang, TJJ Ruiter, JCC Yang, ... CANCER RESEARCH 84 (2), 2024 | | 2024 |
Dr. James D. Johnson, PhDLife Sciences Institute, University of British ColumbiaVerified email at ubc.ca
