Nektar Therapeutics
Verified email at
Cited by
Cited by
Loss of PTEN promotes resistance to T cell–mediated immunotherapy
W Peng, JQ Chen, C Liu, S Malu, C Creasy, MT Tetzlaff, C Xu, ...
Cancer discovery 6 (2), 202-216, 2016
Tumor Regression and Autoimmunity after Reversal of a Functionally Tolerant State of Self-reactive CD8+ T Cells
WW Overwijk, MR Theoret, SE Finkelstein, DR Surman, LA De Jong, ...
The Journal of experimental medicine 198 (4), 569-580, 2003
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
DT Frederick, A Piris, AP Cogdill, ZA Cooper, C Lezcano, CR Ferrone, ...
Clinical cancer research 19 (5), 1225-1231, 2013
CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells
PA Antony, CA Piccirillo, A Akpinarli, SE Finkelstein, PJ Speiss, ...
The Journal of Immunology 174 (5), 2591-2601, 2005
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
N Martin-Orozco, P Muranski, Y Chung, XO Yang, T Yamazaki, S Lu, ...
Immunity 31 (5), 787-798, 2009
Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade
PL Chen, W Roh, A Reuben, ZA Cooper, CN Spencer, PA Prieto, JP Miller, ...
Cancer discovery 6 (8), 827-837, 2016
gp100/pmel 17 is a murine tumor rejection antigen: induction of “self”-reactive, tumoricidal T cells using high-affinity, altered peptide ligand
WW Overwijk, A Tsung, KR Irvine, MR Parkhurst, TJ Goletz, K Tsung, ...
The Journal of experimental medicine 188 (2), 277-286, 1998
B16 as a mouse model for human melanoma
WW Overwijk, NP Restifo
Current protocols in immunology 39 (1), 20.1. 1-20.1. 29, 2000
Vaccination with a recombinant vaccinia virus encoding a “self” antigen induces autoimmune vitiligo and tumor cell destruction in mice: Requirement for CD4+ T …
WW Overwijk, DS Lee, DR Surman, KR Irvine, CE Touloukian, CC Chan, ...
Proceedings of the National Academy of Sciences 96 (6), 2982-2987, 1999
Persistent antigen at vaccination sites induces tumor-specific CD8+ T cell sequestration, dysfunction and deletion
Y Hailemichael, Z Dai, N Jaffarzad, Y Ye, MA Medina, XF Huang, ...
Nature medicine 19 (4), 465-472, 2013
PD-1 blockade enhances T-cell migration to tumors by elevating IFN-γ inducible chemokines
W Peng, C Liu, C Xu, Y Lou, J Chen, Y Yang, H Yagita, WW Overwijk, ...
Cancer research 72 (20), 5209-5218, 2012
Apoptotic death of CD8+ T lymphocytes after immunization: induction of a suppressive population of Mac-1+/Gr-1+ cells
V Bronte, M Wang, WW Overwijk, DR Surman, F Pericle, SA Rosenberg, ...
The Journal of Immunology 161 (10), 5313-5320, 1998
BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice
C Liu, W Peng, C Xu, Y Lou, M Zhang, JA Wargo, JQ Chen, HS Li, ...
Clinical cancer research 19 (2), 393-403, 2013
Plasmacytoid dendritic cells induce NK cell–dependent, tumor antigen–specific T cell cross-priming and tumor regression in mice
C Liu, Y Lou, G Lizée, H Qin, S Liu, B Rabinovich, GJ Kim, YH Wang, Y Ye, ...
The Journal of clinical investigation 118 (3), 1165-1175, 2008
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine …
A van Elsas, RPM Sutmuller, AA Hurwitz, J Ziskin, J Villasenor, ...
The Journal of experimental medicine 194 (4), 481-490, 2001
Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy
TR Hodges, M Ott, J Xiu, Z Gatalica, J Swensen, S Zhou, JT Huse, ...
Neuro-oncology 19 (8), 1047-1057, 2017
Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function
Y Lee, N Martin-Orozco, P Zheng, J Li, P Zhang, H Tan, HJ Park, M Jeong, ...
Cell research 27 (8), 1034-1045, 2017
Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer
BA Rabinovich, Y Ye, T Etto, JQ Chen, HI Levitsky, WW Overwijk, ...
Proceedings of the National Academy of Sciences 105 (38), 14342-14346, 2008
The immune system in cancer metastasis: friend or foe?
LME Janssen, EE Ramsay, CD Logsdon, WW Overwijk
Journal for immunotherapy of cancer 5 (1), 1-14, 2017
Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice
H Qin, B Lerman, I Sakamaki, G Wei, SC Cha, SS Rao, J Qian, ...
Nature medicine 20 (6), 676-681, 2014
The system can't perform the operation now. Try again later.
Articles 1–20