| Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ... Genome biology 21, 1-19, 2020 | 222 | 2020 |
| Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes N Rohani, L Hao, MS Alexis, BA Joughin, K Krismer, MN Moufarrej, ... Cancer research 79 (8), 1952-1966, 2019 | 186 | 2019 |
| Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling J Alexander, D Lim, BA Joughin, B Hegemann, JRA Hutchins, ... Science signaling 4 (179), ra42, 2011 | 186 | 2011 |
| Proteomic identification of 14-3-3ζ as a mitogen-activated protein kinase-activated protein kinase 2 substrate: role in dimer formation and ligand binding DW Powell, MJ Rane, BA Joughin, R Kalmukova, JH Hong, B Tidor, ... Molecular and cellular biology 23 (15), 5376-5387, 2003 | 166 | 2003 |
| Tissue-specific oncogenic activity of KRASA146T EJ Poulin, AK Bera, J Lu, YJ Lin, SD Strasser, JA Paulo, TQ Huang, ... Cancer discovery 9 (6), 738-755, 2019 | 142 | 2019 |
| DNA repair capacity in multiple pathways predicts chemoresistance in glioblastoma multiforme ZD Nagel, GJ Kitange, SK Gupta, BA Joughin, IA Chaim, P Mazzucato, ... Cancer research 77 (1), 198-206, 2017 | 122 | 2017 |
| ROS and oxidative stress are elevated in mitosis during asynchronous cell cycle progression and are exacerbated by mitotic arrest JC Patterson, BA Joughin, B van de Kooij, DC Lim, DA Lauffenburger, ... Cell systems 8 (2), 163-167. e2, 2019 | 100 | 2019 |
| Quantitative phospho-proteomics to investigate the Polo-like kinase 1-dependent phospho-proteome K Grosstessner-Hain, B Hegemann, M Novatchkova, J Rameseder, ... Molecular & Cellular Proteomics 10 (11), 2011 | 87 | 2011 |
| Shank3 mutation in a mouse model of autism leads to changes in the S-nitroso-proteome and affects key proteins involved in vesicle release and synaptic function H Amal, B Barak, V Bhat, G Gong, BA Joughin, X Wang, JS Wishnok, ... Molecular psychiatry 25 (8), 1835-1848, 2020 | 83 | 2020 |
| Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma EC Randall, KB Emdal, JK Laramy, M Kim, A Roos, D Calligaris, ... Nature communications 9 (1), 4904, 2018 | 74 | 2018 |
| Multiplexed relative and absolute quantitative immunopeptidomics reveals MHC I repertoire alterations induced by CDK4/6 inhibition LE Stopfer, JM Mesfin, BA Joughin, DA Lauffenburger, FM White Nature Communications 11 (1), 2760, 2020 | 71 | 2020 |
| A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth CE Meacham, LN Lawton, YM Soto-Feliciano, JR Pritchard, BA Joughin, ... Genes & development 29 (5), 483-488, 2015 | 70 | 2015 |
| Action‐at‐a‐distance interactions enhance protein binding affinity BA Joughin, DF Green, B Tidor Protein science 14 (5), 1363-1369, 2005 | 57 | 2005 |
| A computational method for the analysis and prediction of protein: phosphopeptide‐binding sites BA Joughin, B Tidor, MB Yaffe Protein science 14 (1), 131-139, 2005 | 56 | 2005 |
| PTMScout, a Web resource for analysis of high throughput post-translational proteomics studies KM Naegle, M Gymrek, BA Joughin, JP Wagner, RE Welsch, MB Yaffe, ... Molecular & Cellular Proteomics 9 (11), 2558-2570, 2010 | 47 | 2010 |
| Proteogenomic network analysis of context-specific KRAS signaling in mouse-to-human cross-species translation DK Brubaker, JA Paulo, S Sheth, EJ Poulin, O Popow, BA Joughin, ... Cell systems 9 (3), 258-270. e6, 2019 | 44 | 2019 |
| Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs B Van de Kooij, P Creixell, A van Vlimmeren, BA Joughin, CJ Miller, ... Elife 8, e44635, 2019 | 43 | 2019 |
| PTP1B-dependent regulation of receptor tyrosine kinase signaling by the actin-binding protein Mena SK Hughes, MJ Oudin, J Tadros, J Neil, A Del Rosario, BA Joughin, ... Molecular biology of the cell 26 (21), 3867-3878, 2015 | 39 | 2015 |
| The injury response to DNA damage in live tumor cells promotes antitumor immunity G Sriram, LE Milling, JK Chen, YW Kong, BA Joughin, W Abraham, ... Science signaling 14 (705), eabc4764, 2021 | 35 | 2021 |
| Transite: a computational motif-based analysis platform that identifies RNA-binding proteins modulating changes in gene expression K Krismer, MA Bird, S Varmeh, ED Handly, A Gattinger, T Bernwinkler, ... Cell reports 32 (8), 2020 | 34 | 2020 |
