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Fabio Lapenta
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Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo
A Ljubetič, F Lapenta, H Gradišar, I Drobnak, J Aupič, Ž Strmšek, ...
Nature biotechnology 35 (11), 1094-1101, 2017
1812017
Design of fast proteolysis-based signaling and logic circuits in mammalian cells
T Fink, J Lonzarić, A Praznik, T Plaper, E Merljak, K Leben, N Jerala, ...
Nature chemical biology 15 (2), 115-122, 2019
1522019
Coiled coil protein origami: from modular design principles towards biotechnological applications
F Lapenta, J Aupič, Ž Strmšek, R Jerala
Chemical Society Reviews 47 (10), 3530-3542, 2018
1222018
Structure–activity relationship in monosaccharide-based toll-like receptor 4 (TLR4) antagonists
FA Facchini, L Zaffaroni, A Minotti, S Rapisarda, V Calabrese, M Forcella, ...
Journal of Medicinal Chemistry 61 (7), 2895-2909, 2018
562018
Self-assembly and regulation of protein cages from pre-organised coiled-coil modules
F Lapenta, J Aupič, M Vezzoli, Ž Strmšek, S Da Vela, DI Svergun, ...
Nature communications 12 (1), 939, 2021
362021
Coiled-coil heterodimers with increased stability for cellular regulation and sensing SARS-CoV-2 spike protein-mediated cell fusion
T Plaper, J Aupič, P Dekleva, F Lapenta, MM Keber, R Jerala, M Benčina
Scientific Reports 11 (1), 9136, 2021
232021
A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures
A Majerle, S Hadži, J Aupič, T Satler, F Lapenta, Ž Strmšek, J Lah, R Loris, ...
Proceedings of the National Academy of Sciences 118 (17), e2021899118, 2021
212021
SwitCCh: Metal‐site design for controlling the assembly of a coiled‐coil homodimer
J Aupič, F Lapenta, R Jerala
ChemBioChem 19 (23), 2453-2457, 2018
212018
Escherichia coli DnaE Polymerase Couples Pyrophosphatase Activity to DNA Replication
F Lapenta, A Montón Silva, R Brandimarti, M Lanzi, FL Gratani, ...
PLoS One 11 (4), e0152915, 2016
202016
Designed folding pathway of modular coiled-coil-based proteins
J Aupič, Ž Strmšek, F Lapenta, D Pahovnik, T Pisanski, I Drobnak, ...
Nature communications 12 (1), 940, 2021
162021
Metal ion–regulated assembly of designed modular protein cages
J Aupič, F Lapenta, Ž Strmšek, E Merljak, T Plaper, R Jerala
Science Advances 8 (24), eabm8243, 2022
112022
Design of novel protein building modules and modular architectures
F Lapenta, R Jerala
Current Opinion in Structural Biology 63, 90-96, 2020
92020
Towards designing new nano-scale protein architectures
J Aupič, F Lapenta, Ž Strmšek, R Jerala
Essays in biochemistry 60 (4), 315-324, 2016
82016
HoLaMa: A Klenow sub-fragment lacking the 3′–5′ exonuclease domain
CE Martina, F Lapenta, AM Silva, A Hochkoeppler
Archives of biochemistry and biophysics 575, 46-53, 2015
42015
Simultaneous ternary extension of DNA catalyzed by a trimeric replicase assembled in vivo
AM Silva, F Lapenta, A Stefan, F Dal Piaz, A Ceccarelli, A Perrone, ...
Biochemical and Biophysical Research Communications 462 (1), 14-20, 2015
32015
Intrinsically disordered ectodomain modulates ion permeation through a metal transporter
J Aupič, F Lapenta, P Janoš, A Magistrato
Proceedings of the National Academy of Sciences 119 (48), e2214602119, 2022
12022
De novo designed parallel heterodimeric coiled-coil peptide pairs with high affinity for use in mammalian cells
T Plaper, J Aupic, P Dekleva, F Lapenta, R Jerala, M Bencina
FEBS Open Biol 11, 269, 2021
12021
Preorganized cyclic modules facilitate the self-assembly of protein nanostructures
J Snoj, F Lapenta, R Jerala
Chemical Science, 2024
2024
The avidin‐theophylline complex: A structural and computational study
A Spinello, F Lapenta, M De March
Proteins: Structure, Function, and Bioinformatics 91 (10), 1437-1443, 2023
2023
Contribution of APOBEC proteins 3A and 3B to the oncogenicity of HPV viruses
NM Lovšin, F Lapenta, U Pečar Fonović, K Jazbec, E Maličev, ...
15th Meeting of the Slovenian Biochemical Society with International …, 2023
2023
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