Manganese metabolism in humans P Chen, J Bornhorst, MA Aschner | 473 | 2018 |
Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies TV Peres, MRC Schettinger, P Chen, F Carvalho, DS Avila, AB Bowman, ... BMC Pharmacology and Toxicology 17, 1-20, 2016 | 338 | 2016 |
Metals and neurodegeneration P Chen, MR Miah, M Aschner F1000Research 5, 2016 | 272 | 2016 |
Manganese homeostasis in the nervous system P Chen, S Chakraborty, S Mukhopadhyay, E Lee, MMB Paoliello, ... Journal of neurochemistry 134 (4), 601-610, 2015 | 272 | 2015 |
SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity D Leyva-Illades, P Chen, CE Zogzas, S Hutchens, JM Mercado, ... Journal of Neuroscience 34 (42), 14079-14095, 2014 | 209 | 2014 |
TorsinA participates in endoplasmic reticulum-associated degradation FC Nery, IA Armata, JE Farley, JA Cho, U Yaqub, P Chen, CC Da Hora, ... Nature communications 2 (1), 393, 2011 | 130 | 2011 |
The early-onset torsion dystonia-associated protein, torsinA, is a homeostatic regulator of endoplasmic reticulum stress response P Chen, AJ Burdette, JC Porter, JC Ricketts, SA Fox, FC Nery, JW Hewett, ... Human molecular genetics 19 (18), 3502-3515, 2010 | 111 | 2010 |
Genetic factors and manganese-induced neurotoxicity P Chen, N Parmalee, M Aschner Frontiers in genetics 5, 97129, 2014 | 97 | 2014 |
Metal-induced neurodegeneration in C. elegans P Chen, EJ Martinez-Finley, J Bornhorst, S Chakraborty, M Aschner Frontiers in aging neuroscience 5, 18, 2013 | 92 | 2013 |
Manganese-induced neurotoxicity: from C. elegans to humans P Chen, S Chakraborty, TV Peres, AB Bowman, M Aschner Toxicology research 4 (2), 191-202, 2015 | 83 | 2015 |
Exposure, epidemiology, and mechanism of the environmental toxicant manganese P Chen, M Culbreth, M Aschner Environmental Science and Pollution Research 23, 13802-13810, 2016 | 72 | 2016 |
Chemical enhancement of torsinA function in cell and animal models of torsion dystonia S Cao, JW Hewett, F Yokoi, J Lu, AC Buckley, AJ Burdette, P Chen, ... Disease models & mechanisms 3 (5-6), 386-396, 2010 | 63 | 2010 |
Age- and manganese-dependent modulation of dopaminergic phenotypes in a C. elegans DJ-1 genetic model of Parkinson’s disease P Chen, MR DeWitt, J Bornhorst, FA Soares, S Mukhopadhyay, ... Metallomics 7 (2), 289-298, 2015 | 51 | 2015 |
Mechanisms and disease pathogenesis underlying metal-induced oxidative stress P Chen, J Bornhorst, M Diana Neely, DS Avila Oxidative medicine and cellular longevity 2018, 2018 | 50 | 2018 |
SLC30A10: A novel manganese transporter P Chen, AB Bowman, S Mukhopadhyay, M Aschner Worm 4 (3), e1042648, 2015 | 50 | 2015 |
Iron and manganese-related CNS toxicity: mechanisms, diagnosis and treatment P Chen, M Totten, Z Zhang, H Bucinca, K Erikson, A Santamaría, ... Expert review of neurotherapeutics 19 (3), 243-260, 2019 | 45 | 2019 |
Manganese efflux in Parkinsonism: insights from newly characterized SLC30A10 mutations MR DeWitt, P Chen, M Aschner Biochemical and biophysical research communications 432 (1), 1-4, 2013 | 44 | 2013 |
TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS ML Thompson, P Chen, X Yan, H Kim, AR Borom, NB Roberts, ... Disease models & mechanisms 7 (2), 233-243, 2014 | 42 | 2014 |
PI3K/Akt signaling pathway and Hsp70 activate in hippocampus of rats with chronic manganese sulfate exposure H Cheng, B Xia, C Su, K Chen, X Chen, P Chen, Y Zou, X Yang Journal of Trace Elements in Medicine and Biology 50, 332-338, 2018 | 35 | 2018 |
Loss of pdr-1/parkin influences Mn homeostasis through altered ferroportin expression in C. elegans S Chakraborty, P Chen, J Bornhorst, T Schwerdtle, F Schumacher, ... Metallomics 7 (5), 847-856, 2015 | 30 | 2015 |