Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes. EA Grimm, A Mazumder, HZ Zhang, SA Rosenberg The Journal of experimental medicine 155 (6), 1823-1841, 1982 | 3005 | 1982 |
Integrative analysis identifies four molecular and clinical subsets in uveal melanoma AG Robertson, J Shih, C Yau, EA Gibb, J Oba, KL Mungall, JM Hess, ... Cancer cell 32 (2), 204-220. e15, 2017 | 890 | 2017 |
Biological Activity of Recombinant Human Interleukin-2 Produced in Escherichia coli SA Rosenberg, EA Grimm, M McGrogan, M Doyle, E Kawasaki, K Koths, ... Science 223 (4643), 1412-1415, 1984 | 798 | 1984 |
Lysis of fresh and cultured autologous tumor by human lymphocytes cultured in T-cell growth factor MT Lotze, EA Grimm, A Mazumder, JL Strausser, SA Rosenberg Cancer Research 41 (11_Part_1), 4420-4425, 1981 | 693 | 1981 |
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses SF Hussain, D Yang, D Suki, K Aldape, E Grimm, AB Heimberger Neuro-oncology 8 (3), 261-279, 2006 | 692 | 2006 |
Induction of Chemosensitivity in Human Lung Cancer Cells in Vivo by Adenovirus-mediated Transfer of the Wild-Type p53 Gene T Fujiwara, EA Grimm, T Mukhopadhyay, WW Zhang, LB Owen-Schaub, ... Cancer research 54 (9), 2287-2291, 1994 | 689 | 1994 |
Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and … EA Grimm, KM Ramsey, A Mazumder, DJ Wilson, JY Djeu, SA Rosenberg The Journal of experimental medicine 157 (3), 884-897, 1983 | 613 | 1983 |
Lymphokine-activated killer cell phenomenon. III. Evidence that IL-2 is sufficient for direct activation of peripheral blood lymphocytes into lymphokine-activated killer cells. EA Grimm, RJ Robb, JA Roth, LM Neckers, LB Lachman, DJ Wilson, ... The Journal of experimental medicine 158 (4), 1356-1361, 1983 | 466 | 1983 |
DNA fragmentation and cell death is selectively triggered in activated human lymphocytes by Fas antigen engagement LB Owen-Schaub, S Yonehara, WL Crump III, EA Grimm Cellular Immunology 140 (1), 197-205, 1992 | 448 | 1992 |
The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24 EG Caudell, JB Mumm, N Poindexter, S Ekmekcioglu, AM Mhashilkar, ... The Journal of immunology 168 (12), 6041-6046, 2002 | 438 | 2002 |
Uveal melanoma: From diagnosis to treatment and the science in between C Chattopadhyay, DW Kim, DS Gombos, J Oba, Y Qin, MD Williams, ... Cancer 122 (15), 2299-2312, 2016 | 405 | 2016 |
Oncogenic BRAF (V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma JS Khalili, S Liu, TG Rodríguez-Cruz, M Whittington, S Wardell, C Liu, ... Clinical Cancer Research 18 (19), 5329-5340, 2012 | 327 | 2012 |
Therapeutic effect of a retroviral wild-type p53 expression vector in an orthotopic lung cancer model T Fujiwara, DW Cai, RN Georges, T Mukhopadhyay, EA Grimm, JA Roth JNCI: Journal of the National Cancer Institute 86 (19), 1458-1462, 1994 | 318 | 1994 |
A Retroviral Wild-type p53 Expression Vector Penetrates Human Lung Cancer Spheroids and Inhibits Growth by Inducing Apoptosis T Fujiwara, EA Grimm, T Mukhopadhyay, DW Cai, LB Owen-Schaub, ... Cancer research 53 (18), 4129-4133, 1993 | 318 | 1993 |
Mechanism of cell-mediated cytotoxicity at the single cell level: I. Estimation of cytotoxic T lymphocyte frequency and relative lytic efficiency E Grimm, B Bonavida The Journal of Immunology 123 (6), 2861-2869, 1979 | 316 | 1979 |
Clinical Correlates of NRAS and BRAF Mutations in Primary Human Melanoma JA Ellerhorst, VR Greene, S Ekmekcioglu, CL Warneke, MM Johnson, ... Clinical Cancer Research 17 (2), 229-235, 2011 | 311 | 2011 |
The p75 peptide is the receptor for interleukin 2 expressed on large granular lymphocytes and is responsible for the interleukin 2 activation of these cells. M TsUDO, CK Goldman, KF Bongiovanni, WC Chan, EF Winton, M Yagita, ... Proceedings of the National Academy of Sciences 84 (15), 5394-5398, 1987 | 299 | 1987 |
Intratumoral injection of INGN 241, a nonreplicating adenovector expressing the melanoma-differentiation associated gene-7 (mda-7/IL24): biologic outcome in advanced cancer … AW Tong, J Nemunaitis, D Su, Y Zhang, C Cunningham, N Senzer, ... Molecular therapy 11 (1), 160-172, 2005 | 275 | 2005 |
Genome-wide association study identifies novel loci predisposing to cutaneous melanoma CI Amos, LE Wang, JE Lee, JE Gershenwald, WV Chen, S Fang, R Kosoy, ... Human molecular genetics 20 (24), 5012-5023, 2011 | 271 | 2011 |
Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival S Ekmekcioglu, J Ellerhorst, CM Smid, VG Prieto, M Munsell, AC Buzaid, ... Clinical Cancer Research 6 (12), 4768-4775, 2000 | 266 | 2000 |