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Christian Holland
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Benchmark and integration of resources for the estimation of human transcription factor activities
L Garcia-Alonso, CH Holland, MM Ibrahim, D Turei, J Saez-Rodriguez
Genome research 29 (8), 1363-1375, 2019
3382019
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ...
Genome Biology 21 (1), 36, 2020
1352020
Transfer of regulatory knowledge from human to mouse for functional genomics analysis
CH Holland, B Szalai, J Saez-Rodriguez
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1863 (6), 194431, 2020
722020
Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis
A Mohs, T Otto, KM Schneider, M Peltzer, M Boekschoten, CH Holland, ...
Journal of Hepatology 74 (3), 638-648, 2021
422021
Influence of Liver Fibrosis on Lobular Zonation
A Ghallab, M Myllys, C H Holland, A Zaza, W Murad, R Hassan, ...
Cells 8 (12), 1556, 2019
372019
Signatures of cell death and proliferation in perturbation transcriptomics data—from confounding factor to effective prediction
B Szalai, V Subramanian, CH Holland, R Alföldi, LG Puskás, ...
Nucleic acids research 47 (19), 10010-10026, 2019
362019
decoupleR: Ensemble of computational methods to infer biological activities from omics data
P Badia-i-Mompel, J Vélez Santiago, J Braunger, C Geiss, D Dimitrov, ...
Bioinformatics Advances 2 (1), vbac016, 2022
172022
Spatio-Temporal Multiscale Analysis of Western Diet-Fed Mice Reveals a Translationally Relevant Sequence of Events during NAFLD Progression
A Ghallab, M Myllys, A Friebel, J Duda, K Edlund, E Halilbasic, M Vucur, ...
Cells 10 (10), 2516, 2021
172021
Consensus Transcriptional Landscape of Human End‐Stage Heart Failure
RO Ramirez Flores, JD Lanzer, CH Holland, F Leuschner, P Most, ...
Journal of the American Heart Association 10 (7), e019667, 2021
172021
A functional landscape of CKD entities from public transcriptomic data
F Tajti, C Kuppe, A Antoranz, MM Ibrahim, H Kim, F Ceccarelli, ...
Kidney International Reports 5 (2), 211-224, 2020
12*2020
Imbalanced gut microbiota fuels hepatocellular carcinoma development by shaping the hepatic inflammatory microenvironment
KM Schneider, A Mohs, W Gui, EJC Galvez, LS Candels, L Hoenicke, ...
Nature Communications 13 (1), 3964, 2022
112022
Transcriptomic Cross‐Species Analysis of Chronic Liver Disease Reveals Consistent Regulation Between Humans and Mice
CH Holland, RO Ramirez Flores, M Myllys, R Hassan, K Edlund, ...
Hepatology Communications 6 (1), 161-177, 2022
102022
Stabilization but no functional influence of HIF-1α expression in the intestinal epithelium during Salmonella Typhimurium infection
L Robrahn, A Dupont, S Jumpertz, K Zhang, CH Holland, J Guillaume, ...
Infection and Immunity 90 (2), e00222-21, 2022
32022
Transcription Factor Activity Inference in Systemic Lupus Erythematosus
R Lopez-Dominguez, D Toro-Dominguez, J Martorell-Marugan, ...
Life 11 (4), 299, 2021
22021
FUNKI: interactive functional footprint-based analysis of omics data
R Hernansaiz-Ballesteros, CH Holland, A Dugourd, J Saez-Rodriguez
Bioinformatics 38 (7), 2075-2076, 2022
12022
Novel short-termed mouse model of intrahepatic cholangiocarcinoma by orthotopic transplantation of Hep-55.1 C in mice with human homology
TH Wirtz, EF Brandt, P Fischer, C Holland, A Röth, M Baues, JN May, ...
Zeitschrift für Gastroenterologie 60 (01), P 4.09, 2022
2022
From gene expression to pathway and transcription factor activities to study chronic liver diseases
CH Holland
2021
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Articles 1–17