Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease W Zhou, M Kanai, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, Y Wang, ... Cell Genomics 2 (10), 2022 | 266 | 2022 |
Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD MJ Gandal, JR Haney, B Wamsley, CX Yap, S Parhami, PS Emani, ... Nature 611 (7936), 532-539, 2022 | 136 | 2022 |
An approach for normalization and quality control for NanoString RNA expression data A Bhattacharya, A Hamilton, H Furberg, M Pietzak, Eugene, Purdue, ... Briefings in Bioinformatics, 2020 | 102 | 2020 |
A framework for transcriptome-wide association studies in breast cancer in diverse study populations A Bhattacharya, M García-Closas, AF Olshan, CM Perou, MA Troester, ... Genome biology 21, 1-18, 2020 | 79 | 2020 |
Global Biobank analyses provide lessons for developing polygenic risk scores across diverse cohorts Y Wang, S Namba, E Lopera, S Kerminen, K Tsuo, K Läll, M Kanai, ... Cell Genomics 3 (1), 2023 | 78 | 2023 |
Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals K Hou, Y Ding, Z Xu, Y Wu, A Bhattacharya, R Mester, GM Belbin, ... Nature genetics 55 (4), 549-558, 2023 | 77* | 2023 |
Epigenome-wide DNA methylation in placentas from preterm infants: association with maternal socioeconomic status HP Santos Jr, A Bhattacharya, EM Martin, K Addo, M Psioda, L Smeester, ... Epigenetics 14 (8), 751-765, 2019 | 69 | 2019 |
Multi-ancestry meta-analysis of asthma identifies novel associations and highlights the value of increased power and diversity K Tsuo, W Zhou, Y Wang, M Kanai, S Namba, R Gupta, L Majara, ... Cell genomics 2 (12), 2022 | 63 | 2022 |
Meta-analysis fine-mapping is often miscalibrated at single-variant resolution M Kanai, R Elzur, W Zhou, KHH Wu, H Rasheed, K Tsuo, JB Hirbo, ... Cell genomics 2 (12), 2022 | 63 | 2022 |
MOSTWAS: multi-omic strategies for transcriptome-wide association studies A Bhattacharya, Y Li, MI Love PLoS genetics 17 (3), e1009398, 2021 | 62 | 2021 |
Discrimination exposure and DNA methylation of stress-related genes in Latina mothers HP Santos Jr, BC Nephew, A Bhattacharya, X Tan, L Smith, ... Psychoneuroendocrinology 98, 131-138, 2018 | 53 | 2018 |
Proteome-wide Mendelian randomization in global biobank meta-analysis reveals multi-ancestry drug targets for common diseases H Zhao, H Rasheed, TH Nøst, Y Cho, Y Liu, L Bhatta, A Bhattacharya, ... Cell genomics 2 (11), 2022 | 48 | 2022 |
Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative R Johnson, Y Ding, V Venkateswaran, A Bhattacharya, K Boulier, A Chiu, ... Genome medicine 14 (1), 1-23, 2022 | 42* | 2022 |
A practical guideline of genomics-driven drug discovery in the era of global biobank meta-analysis S Namba, T Konuma, KH Wu, W Zhou, Y Okada Cell Genomics 2 (10), 2022 | 39 | 2022 |
Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm HP Santos Jr, A Bhattacharya, RM Joseph, L Smeester, KCK Kuban, ... Molecular Autism 11, 1-16, 2020 | 39 | 2020 |
Placental genomics mediates genetic associations with complex health traits and disease A Bhattacharya, AN Freedman, V Avula, R Harris, W Liu, C Pan, AJ Lusis, ... Nature communications 13 (1), 706, 2022 | 38 | 2022 |
Leveraging global multi-ancestry meta-analysis in the study of idiopathic pulmonary fibrosis genetics JJ Partanen, P Häppölä, W Zhou, AA Lehisto, M Ainola, E Sutinen, ... Cell genomics 2 (10), 2022 | 35 | 2022 |
Isoform-level transcriptome-wide association uncovers genetic risk mechanisms for neuropsychiatric disorders in the human brain A Bhattacharya, DD Vo, C Jops, M Kim, C Wen, JL Hervoso, B Pasaniuc, ... Nature Genetics 55 (12), 2117-2128, 2023 | 33* | 2023 |
Multi-ancestry genome-wide association study of cannabis use disorder yields insight into disease biology and public health implications DF Levey, M Galimberti, JD Deak, FR Wendt, A Bhattacharya, D Koller, ... Nature Genetics 55 (12), 2094-2103, 2023 | 33 | 2023 |
Single-cell multi-cohort dissection of the schizophrenia transcriptome WB Ruzicka, S Mohammadi, JF Fullard, J Davila-Velderrain, S Subburaju, ... Science 384 (6698), eadg5136, 2024 | 31 | 2024 |