Transgenic mice for intersectional targeting of neural sensors and effectors with high specificity and performance L Madisen, AR Garner, D Shimaoka, AS Chuong, NC Klapoetke, L Li, ... Neuron 85 (5), 942-958, 2015 | 1077 | 2015 |
Cortex-restricted disruption of NMDAR1 impairs neuronal patterns in the barrel cortex T Iwasato, A Datwani, AM Wolf, H Nishiyama, Y Taguchi, S Tonegawa, ... Nature 406 (6797), 726-731, 2000 | 570 | 2000 |
Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? F Nicoletti, V Bruno, A Copani, G Casabona, T Knöpfel Trends in neurosciences 19 (7), 267-271, 1996 | 545 | 1996 |
Potassium conductances in hippocampal neurons blocked by excitatory amino-acid transmitters S Charpak, BH Gähwiler, KQ Do, T Knöpfel Nature 347 (6295), 765-767, 1990 | 497 | 1990 |
Glial protein S100B modulates long-term neuronal synaptic plasticity H Nishiyama, T Knöpfel, S Endo, S Itohara Proceedings of the National Academy of Sciences 99 (6), 4037-4042, 2002 | 380 | 2002 |
Metabotropic glutamate receptors: novel targets for drug development T Knoepfel, R Kuhn, H Allgeier Journal of medicinal chemistry 38 (9), 1417-1426, 1995 | 330 | 1995 |
Imaging brain electric signals with genetically targeted voltage-sensitive fluorescent proteins W Akemann, H Mutoh, A Perron, J Rossier, T Knöpfel Nature methods 7 (8), 643-649, 2010 | 319 | 2010 |
Imaging neural circuit dynamics with a voltage-sensitive fluorescent protein W Akemann, H Mutoh, A Perron, YK Park, Y Iwamoto, T Knöpfel Journal of neurophysiology 108 (8), 2323-2337, 2012 | 289 | 2012 |
Design and characterization of a DNA‐encoded, voltage‐sensitive fluorescent protein R Sakai, V Repunte‐Canonigo, CD Raj, T Knöpfel European Journal of Neuroscience 13 (12), 2314-2318, 2001 | 283 | 2001 |
Genetically encoded optical indicators for the analysis of neuronal circuits T Knöpfel Nature Reviews Neuroscience 13 (10), 687-700, 2012 | 256 | 2012 |
Engineering and characterization of an enhanced fluorescent protein voltage sensor D Dimitrov, Y He, H Mutoh, BJ Baker, L Cohen, W Akemann, T Knöpfel PloS one 2 (5), e440, 2007 | 249 | 2007 |
Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei M Uusisaari, K Obata, T Knopfel Journal of neurophysiology 97 (1), 901-911, 2007 | 247 | 2007 |
Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7 G Sansig, TJ Bushell, VRJ Clarke, A Rozov, N Burnashev, C Portet, ... Journal of Neuroscience 21 (22), 8734-8745, 2001 | 238 | 2001 |
Synaptic integration in a model of cerebellar granule cells F Gabbiani, J Midtgaard, T Knopfel Journal of neurophysiology 72 (2), 999-1009, 1994 | 222 | 1994 |
Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses A Karpova, M Mikhaylova, U Thomas, T Knöpfel, T Behnisch Journal of Neuroscience 26 (18), 4949-4955, 2006 | 220 | 2006 |
Electrotonic coupling of excitable and nonexcitable cells in the heart revealed by optogenetics TA Quinn, P Camelliti, EA Rog-Zielinska, U Siedlecka, T Poggioli, ... Proceedings of the National Academy of Sciences 113 (51), 14852-14857, 2016 | 215 | 2016 |
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells V Bruno, A Copani, T Knöpfel, R Kuhn, G Casabona, P Dell'Albani, ... Neuropharmacology 34 (8), 1089-1098, 1995 | 212 | 1995 |
The Second Intracellular Loop of Metabotropic Glutamate Receptor 1 Cooperates with the Other Intracellular Domains to Control Coupling to G-proteins (∗) J Gomeza, C Joly, R Kuhn, T Knöpfel, J Bockaert, JP Pin Journal of Biological Chemistry 271 (4), 2199-2205, 1996 | 210 | 1996 |
Optical voltage imaging in neurons: moving from technology development to practical tool T Knöpfel, C Song Nature Reviews Neuroscience 20 (12), 719-727, 2019 | 199 | 2019 |
Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements A Lundby, H Mutoh, D Dimitrov, W Akemann, T Knöpfel PloS one 3 (6), e2514, 2008 | 186 | 2008 |