Metallodrugs are unique: opportunities and challenges of discovery and development EJ Anthony, EM Bolitho, HE Bridgewater, OWL Carter, JM Donnelly, ... Chemical science 11 (48), 12888-12917, 2020 | 541 | 2020 |
Top or middle? Up or down? Toward a standard lexicon for protein top-down and allied mass spectrometry approaches F Lermyte, YO Tsybin, PB O’Connor, JA Loo Journal of The American Society for Mass Spectrometry 30 (7), 1149-1157, 2019 | 146 | 2019 |
Higher-order structural characterisation of native proteins and complexes by top-down mass spectrometry M Zhou, C Lantz, KA Brown, Y Ge, L Paša-Tolić, JA Loo, F Lermyte Chemical science 11 (48), 12918-12936, 2020 | 121 | 2020 |
Radical solutions: Principles and application of electron‐based dissociation in mass spectrometry‐based analysis of protein structure F Lermyte, D Valkenborg, JA Loo, F Sobott Mass spectrometry reviews 37 (6), 750-771, 2018 | 110 | 2018 |
Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects J Everett, JF Collingwood, V Tjendana-Tjhin, J Brooks, F Lermyte, ... Nanoscale 10 (25), 11782-11796, 2018 | 109 | 2018 |
ETD allows for native surface mapping of a 150 kDa noncovalent complex on a commercial Q-TWIMS-TOF instrument F Lermyte, A Konijnenberg, JP Williams, JM Brown, D Valkenborg, ... Journal of The American Society for Mass Spectrometry 25 (3), 343-350, 2014 | 107 | 2014 |
Electron transfer dissociation provides higher‐order structural information of native and partially unfolded protein complexes F Lermyte, F Sobott Proteomics 15 (16), 2813-2822, 2015 | 86 | 2015 |
Extensive Charge Reduction and Dissociation of Intact Protein Complexes Following Electron Transfer on a Quadrupole-Ion Mobility-Time-of-Flight MS. F Lermyte, JP Williams, JM Brown, EM Martin, F Sobott Journal of The American Society for Mass Spectrometry 26 (7), 1068-1076, 2015 | 80 | 2015 |
Top-Down Characterization of Denatured Proteins and Native Protein Complexes Using Electron Capture Dissociation Implemented within a Modified Ion Mobility-Mass Spectrometer JP Williams, LJ Morrison, JM Brown, JS Beckman, VG Voinov, F Lermyte Analytical Chemistry 92 (5), 3674-3681, 2020 | 74 | 2020 |
Biogenic metallic elements in the human brain? J Everett, F Lermyte, J Brooks, V Tjendana-Tjhin, G Plascencia-Villa, ... Science Advances 7 (24), eabf6707, 2021 | 73 | 2021 |
Metal Ion Binding to the Amyloid β Monomer Studied by Native Top-Down FTICR Mass Spectrometry F Lermyte, J Everett, YPY Lam, CA Wootton, J Brooks, MP Barrow, ... Journal of The American Society for Mass Spectrometry 30 (10), 2123-2134, 2019 | 68 | 2019 |
Iron stored in ferritin is chemically reduced in the presence of aggregating Aβ (1-42) J Everett, J Brooks, F Lermyte, PB O’Connor, PJ Sadler, J Dobson, ... Scientific Reports 10 (1), 10332, 2020 | 48 | 2020 |
Conformational Space and Stability of ETD Charge Reduction Products of Ubiquitin. F Lermyte, MK Łącki, D Valkenborg, A Gambin, F Sobott Journal of The American Society for Mass Spectrometry 28 (1), 69-76, 2017 | 38 | 2017 |
Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1 M Heirbaut, F Lermyte, EM Martin, S Beelen, F Sobott, SV Strelkov, ... Journal of Biological Chemistry 292 (24), 9944-9957, 2017 | 35 | 2017 |
Characterization of top-down ETD in a travelling-wave ion guide F Lermyte, T Verschueren, JM Brown, JP Williams, D Valkenborg, ... Methods 89, 22-29, 2015 | 32 | 2015 |
The preferential heterodimerization of human small heat shock proteins HSPB1 and HSPB6 is dictated by the N-terminal domain M Heirbaut, F Lermyte, EM Martin, S Beelen, T Verschueren, F Sobott, ... Archives of biochemistry and biophysics 610, 41-50, 2016 | 30 | 2016 |
Gas-phase microsolvation of ubiquitin: investigation of crown ether complexation sites using ion mobility-mass spectrometry M Göth, F Lermyte, XJ Schmitt, S Warnke, G von Helden, F Sobott, ... Analyst 141 (19), 5502-5510, 2016 | 26 | 2016 |
Understanding reaction pathways in top-down ETD by dissecting isotope distributions: A mammoth task F Lermyte, MK Łącki, D Valkenborg, G Baggerman, A Gambin, F Sobott International Journal of Mass Spectrometry 390, 146-154, 2015 | 26 | 2015 |
Roles, Characteristics, and Analysis of Intrinsically Disordered Proteins: A Minireview F Lermyte Life 10 (12), 320, 2020 | 25 | 2020 |
Emerging Approaches to Investigate the Influence of Transition Metals in the Proteinopathies F Lermyte, J Everett, J Brooks, F Bellingeri, K Billimoria, PJ Sadler, ... Cells 8 (10), 1231, 2019 | 25 | 2019 |