| Phenylalanine-508 mediates a cytoplasmic–membrane domain contact in the CFTR 3D structure crucial to assembly and channel function AWR Serohijos, T Hegedűs, AA Aleksandrov, L He, L Cui, NV Dokholyan, ... Proceedings of the National Academy of Sciences 105 (9), 3256-3261, 2008 | 439 | 2008 |
| Protein quality control acts on folding intermediates to shape the effects of mutations on organismal fitness S Bershtein, W Mu, AWR Serohijos, J Zhou, EI Shakhnovich Molecular cell 49 (1), 133-144, 2013 | 180 | 2013 |
| Protein folding: then and now Y Chen, F Ding, H Nie, AW Serohijos, S Sharma, KC Wilcox, S Yin, ... Archives of biochemistry and biophysics 469 (1), 4-19, 2008 | 151 | 2008 |
| Multiple membrane-cytoplasmic domain contacts in the cystic fibrosis transmembrane conductance regulator (CFTR) mediate regulation of channel gating L He, AA Aleksandrov, AWR Serohijos, T Hegedus, LA Aleksandrov, ... Journal of Biological Chemistry 283 (39), 26383-26390, 2008 | 130 | 2008 |
| Protein biophysics explains why highly abundant proteins evolve slowly AWR Serohijos, Z Rimas, EI Shakhnovich Cell reports 2 (2), 249-256, 2012 | 104 | 2012 |
| Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics AWR Serohijos, EI Shakhnovich Current opinion in structural biology 26, 84-91, 2014 | 87 | 2014 |
| Protein homeostasis imposes a barrier on functional integration of horizontally transferred genes in bacteria S Bershtein, AWR Serohijos, S Bhattacharyya, M Manhart, JM Choi, W Mu, ... PLoS genetics 11 (10), e1005612, 2015 | 77 | 2015 |
| Identification and rational redesign of peptide ligands to CRIP1, a novel biomarker for cancers J Hao, AWR Serohijos, G Newton, G Tassone, Z Wang, DC Sgroi, ... PLoS computational biology 4 (8), e1000138, 2008 | 75 | 2008 |
| Bridging the physical scales in evolutionary biology: from protein sequence space to fitness of organisms and populations S Bershtein, AWR Serohijos, EI Shakhnovich Current opinion in structural biology 42, 31-40, 2017 | 69 | 2017 |
| Computational studies reveal phosphorylation-dependent changes in the unstructured R domain of CFTR T Hegedűs, AWR Serohijos, NV Dokholyan, L He, JR Riordan Journal of molecular biology 378 (5), 1052-1063, 2008 | 65 | 2008 |
| Positively selected sites in cetacean myoglobins contribute to protein stability P Dasmeh, AWR Serohijos, KP Kepp, EI Shakhnovich PLoS Computational Biology 9 (3), e1002929, 2013 | 56 | 2013 |
| Diminished self-chaperoning activity of the ΔF508 mutant of CFTR results in protein misfolding AWR Serohijos, T Hegedűs, JR Riordan, NV Dokholyan PLoS Computational Biology 4 (2), e1000008, 2008 | 54 | 2008 |
| Influenza A H1N1 pandemic strain evolution–divergence and the potential for antigenic drift variants EY Klein, AWR Serohijos, JM Choi, EI Shakhnovich, A Pekosz PloS one 9 (4), e93632, 2014 | 51 | 2014 |
| Contribution of selection for protein folding stability in shaping the patterns of polymorphisms in coding regions AWR Serohijos, EI Shakhnovich Molecular biology and evolution 31 (1), 165-176, 2014 | 47 | 2014 |
| The Influence of Selection for Protein Stability on dN/dS Estimations P Dasmeh, AWR Serohijos, KP Kepp, EI Shakhnovich Genome biology and evolution 6 (10), 2956-2967, 2014 | 46 | 2014 |
| A structural model reveals energy transduction in dynein AWR Serohijos, Y Chen, F Ding, TC Elston, NV Dokholyan Proceedings of the National Academy of Sciences 103 (49), 18540-18545, 2006 | 42 | 2006 |
| Structural basis for μ-opioid receptor binding and activation AWR Serohijos, S Yin, F Ding, J Gauthier, DG Gibson, W Maixner, ... Structure 19 (11), 1683-1690, 2011 | 38 | 2011 |
| Highly abundant proteins favor more stable 3D structures in yeast AWR Serohijos, SYR Lee, EI Shakhnovich Biophysical journal 104 (3), L1-L3, 2013 | 36 | 2013 |
| Evolution on the biophysical fitness landscape of an RNA virus A Rotem, AWR Serohijos, CB Chang, JT Wolfe, AE Fischer, TS Mehoke, ... Molecular biology and evolution 35 (10), 2390-2400, 2018 | 34 | 2018 |
| Isolation and analysis of rare norovirus recombinants from coinfected mice using drop-based microfluidics H Zhang, SK Cockrell, AO Kolawole, A Rotem, AWR Serohijos, CB Chang, ... Journal of virology 89 (15), 7722-7734, 2015 | 33 | 2015 |
Nikolay DokholyanG. Thomas Passananti ProfessorVerified email at psu.edu
