α-Synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models AA Cooper, AD Gitler, A Cashikar, CM Haynes, KJ Hill, B Bhullar, K Liu, ... Science 313 (5785), 324-328, 2006 | 1689 | 2006 |
Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model S Hamamichi, RN Rivas, AL Knight, S Cao, KA Caldwell, GA Caldwell Proceedings of the National Academy of Sciences 105 (2), 728-733, 2008 | 354 | 2008 |
Torsin-mediated protection from cellular stress in the dopaminergic neurons of Caenorhabditis elegans S Cao, CC Gelwix, KA Caldwell, GA Caldwell Journal of Neuroscience 25 (15), 3801-3812, 2005 | 326 | 2005 |
Deletion of the ubiquitin ligase CHIP leads to the accumulation, but not the aggregation, of both endogenous phospho-and caspase-3-cleaved tau species CA Dickey, M Yue, WL Lin, DW Dickson, JH Dunmore, WC Lee, C Zehr, ... Journal of Neuroscience 26 (26), 6985-6996, 2006 | 288 | 2006 |
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models LJ Su, PK Auluck, TF Outeiro, E Yeger-Lotem, JA Kritzer, DF Tardiff, ... Disease models & mechanisms 3 (3-4), 194-208, 2010 | 218 | 2010 |
Suppression of polyglutamine-induced protein aggregation in Caenorhabditis elegans by torsin proteins GA Caldwell, S Cao, EG Sexton, CC Gelwix, JP Bevel, KA Caldwell Human molecular genetics 12 (3), 307-319, 2003 | 168 | 2003 |
Chemical enhancement of torsinA function in cell and animal models of torsion dystonia S Cao, JW Hewett, F Yokoi, J Lu, AC Buckley, AJ Burdette, P Chen, ... Disease models & mechanisms 3 (5-6), 386-396, 2010 | 63 | 2010 |
Methods of using small molecule compounds for neuroprotection G Caldwell, K Caldwell, S Cao US Patent App. 11/603,924, 2007 | 19 | 2007 |
An animal model to discern torsin function: suppression of protein aggregation in C. elegans GA Caldwell, S Cao, CC Gelwix, EG Sexton, KA Caldwell Advances in neurology 94, 79-85, 2004 | 9 | 2004 |
Use of C. elegans to model human movement disorders GA Caldwell, S Cao, I Izevbaye, KA Caldwell Animal Models of Movement Disorders. LeDoux MS (Ed.), Burlington, USA …, 2005 | 4 | 2005 |
Functional characterization of torsins in Caenorhabditis elegans models of human neurological movement disorders S Cao The University of Alabama, 2006 | | 2006 |
Systematic RNAi screening for effectors of alpha-synuclein folding and degradation in C-elegans KA Caldwell, SB Fulghum, S Cao, GA Caldwell MOVEMENT DISORDERS 19, S227-S227, 2004 | | 2004 |
II Oppenheim's Dystonia-11 An Animal Model to Discern Torsin Function: Suppression of Protein Aggregation in C. elegans GA Caldwell, S Cao, CC Gelwix, EG Sexton, KA Caldwell Advances in Neurology 10, 79-86, 2004 | | 2004 |
Use of C-elegans to examine factors influencing alpha-synuclein aggregation SB Adair, S Cao, CC Gelwix, KA Caldwell, GA Caldwell MOLECULAR BIOLOGY OF THE CELL 13, 515A-515A, 2002 | | 2002 |
Suppression of polyglutamine induced protein aggregation in C-elegans by torsin proteins: Searching for potential therapeutics for neurological diseases S Cao, CC Gelwix, EG Sexton, D Wyatt, KA Caldwell, GA Caldwell MOLECULAR BIOLOGY OF THE CELL 13, 237A-237A, 2002 | | 2002 |