Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation M Nakaya, Y Xiao, X Zhou, JH Chang, M Chang, X Cheng, M Blonska, ... Immunity 40 (5), 692-705, 2014 | 843 | 2014 |
USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses Q Zou, J Jin, H Hu, HS Li, S Romano, Y Xiao, M Nakaya, X Zhou, X Cheng, ... Nature immunology 15 (6), 562-570, 2014 | 247 | 2014 |
The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity M Chang, W Jin, JH Chang, Y Xiao, GC Brittain, J Yu, X Zhou, YH Wang, ... Nature immunology 12 (10), 1002-1009, 2011 | 206 | 2011 |
Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation Y Xiao, J Jin, M Chang, JH Chang, H Hu, X Zhou, GC Brittain, ... Nature medicine 19 (5), 595-602, 2013 | 205 | 2013 |
Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells JH Chang, Y Xiao, H Hu, J Jin, J Yu, X Zhou, X Wu, HM Johnson, S Akira, ... Nature immunology 13 (5), 481-490, 2012 | 140 | 2012 |
Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation J Yu, X Zhou, M Chang, M Nakaya, JH Chang, Y Xiao, J William Lindsey, ... Nature communications 6 (1), 6074, 2015 | 113 | 2015 |
Regulation of Th17 cell differentiation and EAE induction by MAP3K NIK W Jin, XF Zhou, J Yu, X Cheng, SC Sun Blood, The Journal of the American Society of Hematology 113 (26), 6603-6610, 2009 | 107 | 2009 |
The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming X Zhou, J Yu, X Cheng, B Zhao, GC Manyam, L Zhang, K Schluns, P Li, ... Nature immunology 20 (7), 879-889, 2019 | 84 | 2019 |
NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity M Gu, X Zhou, JH Sohn, L Zhu, Z Jie, JY Yang, X Zheng, X Xie, J Yang, ... Nature immunology 22 (2), 193-204, 2021 | 83 | 2021 |
TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis L Zhu, Y Li, X Xie, X Zhou, M Gu, Z Jie, CJ Ko, T Gao, BE Hernandez, ... Nature cell biology 21 (12), 1604-1614, 2019 | 78 | 2019 |
TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling Y Xiao, J Jin, M Chang, M Nakaya, H Hu, Q Zou, X Zhou, GC Brittain, ... Journal of Experimental Medicine 211 (8), 1689-1702, 2014 | 76 | 2014 |
Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses Y Li, H Wang, X Zhou, X Xie, X Chen, Z Jie, Q Zou, H Hu, L Zhu, X Cheng, ... Scientific reports 6 (1), 22115, 2016 | 67 | 2016 |
Targeting ubiquitin signaling for cancer immunotherapy X Zhou, SC Sun Signal transduction and targeted therapy 6 (1), 16, 2021 | 60 | 2021 |
T cell–intrinsic function of the noncanonical NF-κB pathway in the regulation of GM-CSF expression and experimental autoimmune encephalomyelitis pathogenesis J Yu, X Zhou, M Nakaya, W Jin, X Cheng, SC Sun The Journal of Immunology 193 (1), 422-430, 2014 | 57 | 2014 |
T cell intrinsic USP15 deficiency promotes excessive IFN-γ production and an immunosuppressive tumor microenvironment in MCA-induced fibrosarcoma Q Zou, J Jin, Y Xiao, X Zhou, H Hu, X Cheng, N Kazimi, SE Ullrich, ... Cell reports 13 (11), 2470-2479, 2015 | 53 | 2015 |
TRIM28 mediates chromatin modifications at the TCRα enhancer and regulates the development of T and natural killer T cells XF Zhou, J Yu, M Chang, M Zhang, D Zhou, F Cammas, SC Sun Proceedings of the National Academy of Sciences 109 (49), 20083-20088, 2012 | 47 | 2012 |
Preventing abnormal NF-κB activation and autoimmunity by Otub1-mediated p100 stabilization Y Li, JY Yang, X Xie, Z Jie, L Zhang, J Shi, D Lin, M Gu, X Zhou, HS Li, ... Cell research 29 (6), 474-485, 2019 | 44 | 2019 |
NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis Z Jie, JY Yang, M Gu, H Wang, X Xie, Y Li, T Liu, L Zhu, J Shi, L Zhang, ... Nature immunology 19 (11), 1224-1235, 2018 | 43 | 2018 |
Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination L Zhang, CJ Ko, Y Li, Z Jie, L Zhu, X Zhou, X Xie, T Gao, T Liu, X Cheng, ... Cell Reports 37 (4), 2021 | 42 | 2021 |
CARMA1 regulation of regulatory T cell development involves modulation of interleukin-2 receptor signaling AJ Lee, X Wu, H Cheng, X Zhou, X Cheng, SC Sun Journal of Biological Chemistry 285 (21), 15696-15703, 2010 | 42 | 2010 |