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Xinlai Cheng
Xinlai Cheng
Verified email at pharmchem.uni-frankfurt.de
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Cited by
Year
A TrxR inhibiting gold (I) NHC complex induces apoptosis through ASK1-p38-MAPK signaling in pancreatic cancer cells
X Cheng, P Holenya, S Can, H Alborzinia, R Rubbiani, I Ott, S Wölfl
Molecular cancer 13, 1-15, 2014
1202014
Liver-kidney-on-chip to study toxicity of drug metabolites
J Theobald, A Ghanem, P Wallisch, AA Banaeiyan, MA Andrade-Navarro, ...
ACS biomaterials science & engineering 4 (1), 78-89, 2018
1112018
Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic …
S Nam, W Wen, A Schroeder, A Herrmann, H Yu, X Cheng, KH Merz, ...
Molecular oncology 7 (3), 369-378, 2013
932013
Indirubin derivatives induce apoptosis of chronic myelogenous leukemia cells involving inhibition of Stat5 signaling
S Nam, A Scuto, F Yang, WY Chen, S Park, HS Yoo, H Konig, R Bhatia, ...
Molecular oncology 6 (3), 276-283, 2012
882012
Natural lignans from Arctium lappa modulate P-glycoprotein efflux function in multidrug resistant cancer cells
S Su, X Cheng, M Wink
Phytomedicine 22 (2), 301-307, 2015
692015
Detailed analysis of pro-apoptotic signaling and metabolic adaptation triggered by a N-heterocyclic carbene–gold(i) complex
P Holenya, S Can, R Rubbiani, H Alborzinia, A Jünger, X Cheng, I Ott, ...
Metallomics 6 (9), 1591-1601, 2014
592014
Enhancement of oral bioavailability of E804 by self-nanoemulsifying drug delivery system (SNEDDS) in rats
N Heshmati, X Cheng, G Eisenbrand, G Fricker
Journal of Pharmaceutical Sciences 102 (10), 3792-3799, 2013
592013
Quantitative kinetics analysis of BMP2 uptake into cells and its modulation by BMP antagonists
H Alborzinia, H Schmidt-Glenewinkel, I Ilkavets, K Breitkopf-Heinlein, ...
Journal of cell science 126 (1), 117-127, 2013
552013
Fluorescent organometallic rhodium (I) and ruthenium (II) metallodrugs with 4-ethylthio-1, 8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction
W Streciwilk, A Terenzi, X Cheng, L Hager, Y Dabiri, P Prochnow, ...
European Journal of Medicinal Chemistry 156, 148-161, 2018
542018
Synthesis and cytotoxicity of novel indirubin-5-carboxamides
X Cheng, P Rasqué, S Vatter, KH Merz, G Eisenbrand
Bioorganic & medicinal chemistry 18 (12), 4509-4515, 2010
512010
Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs
X Cheng, JY Kim, S Ghafoory, T Duvaci, R Rafiee, J Theobald, ...
Molecular oncology 10 (6), 806-824, 2016
462016
In vitro metabolic activation of vitamin D3 by using a multi-compartment microfluidic liver-kidney organ on chip platform
J Theobald, MA Abu el Maaty, N Kusterer, B Wetterauer, M Wink, X Cheng, ...
Scientific reports 9 (1), 4616, 2019
452019
Essential role of mitochondrial Stat3 in p38MAPK mediated apoptosis under oxidative stress
X Cheng, C Peuckert, S Wölfl
Scientific reports 7 (1), 15388, 2017
452017
Identification of a water-soluble indirubin derivative as potent inhibitor of insulin-like growth factor 1 receptor through structural modification of the parent natural molecule
X Cheng, KH Merz, S Vatter, J Zeller, S Muehlbeyer, A Thommet, J Christ, ...
Journal of Medicinal Chemistry 60 (12), 4949-4962, 2017
412017
7, 7′-diazaindirubin—a small molecule inhibitor of casein kinase 2 in vitro and in cells
X Cheng, KH Merz, S Vatter, J Christ, S Wölfl, G Eisenbrand
Bioorganic & medicinal chemistry 22 (1), 247-255, 2014
412014
Indirubin derivatives modulate TGFβ/BMP signaling at different levels and trigger ubiquitin-mediated depletion of nonactivated R-Smads
X Cheng, H Alborzinia, KH Merz, H Steinbeisser, R Mrowka, C Scholl, ...
Chemistry & Biology 19 (11), 1423-1436, 2012
412012
p53-Dependent Anti-Proliferative and Pro-Apoptotic Effects of a Gold(I) N-Heterocyclic Carbene (NHC) Complex in Colorectal Cancer Cells
Y Dabiri, MA Abu el Maaty, HY Chan, J Wölker, I Ott, S Wölfl, X Cheng
Frontiers in oncology 9, 438, 2019
402019
Pro-oxidant and lifespan extension effects of caffeine and related methylxanthines in Caenorhabditis elegans
H Li, M Roxo, X Cheng, S Zhang, H Cheng, M Wink
Food chemistry: X 1, 100005, 2019
382019
A Ruthenium(II) N-Heterocyclic Carbene (NHC) Complex with Naphthalimide Ligand Triggers Apoptosis in Colorectal Cancer Cells via Activating the ROS-p38 …
Y Dabiri, A Schmid, J Theobald, B Blagojevic, W Streciwilk, I Ott, S Wölfl, ...
International Journal of Molecular Sciences 19 (12), 3964, 2018
332018
Cytotoxicity of arctigenin and matairesinol against the T-cell lymphoma cell line CCRF-CEM
S Su, X Cheng, M Wink
Journal of Pharmacy and Pharmacology 67 (9), 1316-1323, 2015
302015
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