Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines V Swaminathan, K Mythreye, ET O'Brien, A Berchuck, GC Blobe, ... Cancer research 71 (15), 5075-5080, 2011 | 847 | 2011 |
The Type III TGF-beta Receptor Regulates Epithelial and Cancer Cell Migration Through beta-arrestin2-mediated Activation of Cdc42 K Mythreye, GC Blobe Proc Natl Acad Sci U S A 106 (no. 20), 8221-8226, 2009 | 168 | 2009 |
Insights into the Dichotomous Regulation of SOD2 in Cancer YS Kim, P Gupta Vallur, R Phaėton, K Mythreye, N Hempel Antioxidants 6 (4), 86, 2017 | 165 | 2017 |
Proteoglycan signaling co-receptors: roles in cell adhesion, migration and invasion K Mythreye, GC Blobe Cellular signalling 21 (11), 1548-1558, 2009 | 165 | 2009 |
Reactive oxygen species in vascular endothelial cell motility. Roles of NAD (P) H oxidase and Rac1 L Moldovan, K Mythreye, PJ Goldschmidt-Clermont, LL Satterwhite Cardiovascular research 71 (2), 236-246, 2006 | 146 | 2006 |
Endoglin mediates fibronectin/α5β1 integrin and TGF‐β pathway crosstalk in endothelial cells H Tian, K Mythreye, C Golzio, N Katsanis, GC Blobe The EMBO journal 31 (19), 3885-3900, 2012 | 106 | 2012 |
The microtubule-based motor Kar3 and plus end–binding protein Bim1 provide structural support for the anaphase spindle MK Gardner, J Haase, K Mythreye, JN Molk, MB Anderson, AP Joglekar, ... The Journal of Cell Biology 180 (1), 91-100, 2008 | 94 | 2008 |
CDK8 selectively promotes the growth of colon cancer metastases in the liver by regulating gene expression of TIMP3 and matrix metalloproteinases J Liang, M Chen, D Hughes, AA Chumanevich, S Altilia, V Kaza, CU Lim, ... Cancer research 78 (23), 6594-6606, 2018 | 93 | 2018 |
The type III transforming growth factor-β receptor inhibits proliferation, migration, and adhesion in human myeloma cells KE Lambert, H Huang, K Mythreye, GC Blobe Molecular biology of the cell 22 (9), 1463-1472, 2011 | 75 | 2011 |
Mediator kinase CDK8/CDK19 drives YAP1-dependent BMP4-induced EMT in cancer A Serrao, LM Jenkins, AA Chumanevich, B Horst, J Liang, ML Gatza, ... Oncogene 37 (35), 4792-4808, 2018 | 62 | 2018 |
TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion LD Osborne, GZ Li, T How, ET O'Brien, GC Blobe, R Superfine, ... Molecular biology of the cell 25 (22), 3528-3540, 2014 | 61 | 2014 |
GPx3 supports ovarian cancer progression by manipulating the extracellular redox environment BL Worley, YS Kim, J Mardini, R Zaman, KE Leon, PG Vallur, ... Redox biology 25, 101051, 2019 | 55 | 2019 |
TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth N Shah, S Kumar, N Zaman, CC Pan, JC Bloodworth, W Lei, JM Streicher, ... Nature communications 9 (1), 1696, 2018 | 52 | 2018 |
Activation of Mitofusin2 by Smad2-RIN1 complex during mitochondrial fusion S Kumar, CC Pan, N Shah, SE Wheeler, KR Hoyt, N Hempel, K Mythreye, ... Molecular cell 62 (4), 520-531, 2016 | 52 | 2016 |
Type III TGF-β receptor promotes FGF2-mediated neuronal differentiation in neuroblastoma EH Knelson, AL Gaviglio, AK Tewari, MB Armstrong, K Mythreye, ... The Journal of clinical investigation 123 (11), 4786-4798, 2013 | 50 | 2013 |
TGFβ signaling networks in ovarian cancer progression and plasticity A Kumari, Z Shonibare, M Monavarian, RC Arend, NY Lee, GJ Inman, ... Clinical & Experimental Metastasis 38, 139-161, 2021 | 49 | 2021 |
Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells YS Kim, P Gupta Vallur, VM Jones, BL Worley, S Shimko, DH Shin, ... Oncogene 39 (8), 1619-1633, 2020 | 46 | 2020 |
TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells K Mythreye, EH Knelson, CE Gatza, ML Gatza, GC Blobe Oncogene 32 (11), 1416-1427, 2013 | 46 | 2013 |
Endoglin regulation of Smad2 function mediates Beclin1 expression and endothelial autophagy CC Pan, S Kumar, N Shah, JC Bloodworth, LJAC Hawinkels, K Mythreye, ... Journal of Biological Chemistry 290 (24), 14884-14892, 2015 | 45 | 2015 |
Inhibin is a novel paracrine factor for tumor angiogenesis and metastasis P Singh, LM Jenkins, B Horst, V Alers, S Pradhan, P Kaur, T Srivastava, ... Cancer research 78 (11), 2978-2989, 2018 | 41 | 2018 |