| The polycystic kidney-disease-1 gene encodes a 14-Kb transcript and lies within a duplicated region on chromosome-16 CJ Ward, B Peral, J Hughes, S Thomas, V Gamble, AB MacCarthy, ... Cell 77 (6), 881-894, 1994 | 776 | 1994 |
| RYBP-PRC1 complexes mediate H2A ubiquitylation at polycomb target sites independently of PRC2 and H3K27me3 L Tavares, E Dimitrova, D Oxley, J Webster, R Poot, J Demmers, ... Cell 148 (4), 664-678, 2012 | 665 | 2012 |
| Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment JR Hughes, N Roberts, S McGowan, D Hay, E Giannoulatou, M Lynch, ... Nature genetics 46 (2), 205-212, 2014 | 514 | 2014 |
| ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner MJ Law, KM Lower, HPJ Voon, JR Hughes, D Garrick, V Viprakasit, ... Cell 143 (3), 367-378, 2010 | 459 | 2010 |
| Ontology-based Tools for Knowledge Management. DA Fensel, FAH van Harmelen, JM Akkermans, M Klein, J Broekstra, ... eBusiness and eWork 2000 (EMMSEC 2000) Conference, Madrid, Spain, 1105-1110, 2000 | 400* | 2000 |
| A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter M De Gobbi, V Viprakasit, JR Hughes, C Fisher, VJ Buckle, H Ayyub, ... Science 312 (5777), 1215-1217, 2006 | 361 | 2006 |
| Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo PS Woll, U Kjällquist, O Chowdhury, H Doolittle, DC Wedge, S Thongjuea, ... Cancer cell 25 (6), 794-808, 2014 | 355 | 2014 |
| Intragenic enhancers act as alternative promoters MS Kowalczyk, JR Hughes, D Garrick, MD Lynch, JA Sharpe, ... Molecular cell 45 (4), 447-458, 2012 | 313 | 2012 |
| Association between active genes occurs at nuclear speckles and is modulated by chromatin environment JM Brown, J Green, RP das Neves, HAC Wallace, AJH Smith, J Hughes, ... The Journal of cell biology 182 (6), 1083-1097, 2008 | 301 | 2008 |
| Suppression of the alternative lengthening of telomere pathway by the chromatin remodelling factor ATRX D Clynes, C Jelinska, B Xella, H Ayyub, C Scott, M Mitson, S Taylor, ... Nature communications 6 (1), 7538, 2015 | 294 | 2015 |
| Multiplexed analysis of chromosome conformation at vastly improved sensitivity JOJ Davies, JM Telenius, SJ McGowan, NA Roberts, S Taylor, DR Higgs, ... Nature methods 13 (1), 74, 2016 | 277 | 2016 |
| Erythroferrone inhibits the induction of hepcidin by BMP6 J Arezes, N Foy, K McHugh, A Sawant, D Quinkert, V Terraube, A Brinth, ... Blood, The Journal of the American Society of Hematology 132 (14), 1473-1477, 2018 | 246 | 2018 |
| Expression of microRNAs in diffuse large B cell lymphoma is associated with immunophenotype, survival and transformation from follicular lymphoma CH Lawrie, J Chi, S Taylor, D Tramonti, E Ballabio, S Palazzo, ... Journal of cellular and molecular medicine 13 (7), 1248-1260, 2009 | 238 | 2009 |
| Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization CA Brackley, S Taylor, A Papantonis, PR Cook, D Marenduzzo Proceedings of the National Academy of Sciences 110 (38), E3605-E3611, 2013 | 233 | 2013 |
| Genome-wide identification of TAL1's functional targets: insights into its mechanisms of action in primary erythroid cells MT Kassouf, JR Hughes, S Taylor, SJ McGowan, S Soneji, AL Green, ... Genome research 20 (8), 1064-1083, 2010 | 222 | 2010 |
| Tissue-specific CTCF–cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo LLP Hanssen, MT Kassouf, AM Oudelaar, D Biggs, C Preece, DJ Downes, ... Nature cell biology 19 (8), 952-961, 2017 | 213 | 2017 |
| Impact of spliceosome mutations on RNA splicing in myelodysplasia: dysregulated genes/pathways and clinical associations A Pellagatti, RN Armstrong, V Steeples, E Sharma, E Repapi, S Singh, ... Blood, The Journal of the American Society of Hematology 132 (12), 1225-1240, 2018 | 201 | 2018 |
| Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level G Swiers, C Baumann, J O’Rourke, E Giannoulatou, S Taylor, A Joshi, ... Nature communications 4 (1), 2924, 2013 | 200 | 2013 |
| Annotation of cis-regulatory elements by identification, subclassification, and functional assessment of multispecies conserved sequences JR Hughes, JF Cheng, N Ventress, S Prabhakar, K Clark, E Anguita, ... Proceedings of the National Academy of Sciences 102 (28), 9830-9835, 2005 | 183 | 2005 |
| ATRX plays a key role in maintaining silencing at interstitial heterochromatic loci and imprinted genes HPJ Voon, JR Hughes, C Rode, A Inti, T Jenuwein, R Feil, DR Higgs, ... Cell reports 11 (3), 405-418, 2015 | 180 | 2015 |
