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Kilian V. M. Huber
Kilian V. M. Huber
Principal Investigator, University of Oxford
Verified email at cmd.ox.ac.uk - Homepage
Title
Cited by
Cited by
Year
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
8412015
SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1
M Rebsamen, L Pochini, T Stasyk, MEG De Araújo, M Galluccio, ...
Nature 519 (7544), 477-481, 2015
6902015
Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
KVM Huber, E Salah, B Radic, M Gridling, JM Elkins, A Stukalov, ...
Nature 508 (7495), 222-227, 2014
4422014
PIM serine/threonine kinases in the pathogenesis and therapy of hematologic malignancies and solid cancers
L Brault, C Gasser, F Bracher, K Huber, S Knapp, J Schwaller
haematologica 95 (6), 1004, 2010
4232010
Artemisinins target GABAA receptor signaling and impair α cell identity
J Li, T Casteels, T Frogne, C Ingvorsen, C Honore, M Courtney, ...
Cell 168 (1), 86-100. e15, 2017
3852017
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
F Grebien, M Vedadi, M Getlik, R Giambruno, A Grover, R Avellino, ...
Nature chemical biology 11 (8), 571-578, 2015
2872015
Rapid covalent-probe discovery by electrophile-fragment screening
E Resnick, A Bradley, J Gan, A Douangamath, T Krojer, R Sethi, ...
Journal of the American Chemical Society 141 (22), 8951-8968, 2019
2482019
Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing
O Fedorov, K Huber, A Eisenreich, P Filippakopoulos, O King, AN Bullock, ...
Chemistry & biology 18 (1), 67-76, 2011
2232011
Quantitative, wide-spectrum kinase profiling in live cells for assessing the effect of cellular ATP on target engagement
JD Vasta, CR Corona, J Wilkinson, CA Zimprich, JR Hartnett, MR Ingold, ...
Cell chemical biology 25 (2), 206-214. e11, 2018
2192018
Proteome-wide drug and metabolite interaction mapping by thermal-stability profiling
KVM Huber, KM Olek, AC Müller, CSH Tan, KL Bennett, J Colinge, ...
Nature methods 12 (11), 1055-1057, 2015
2142015
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis
A Fauster, M Rebsamen, KVM Huber, JW Bigenzahn, A Stukalov, ...
Cell death & disease 6 (5), e1767-e1767, 2015
1942015
The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity
GE Winter, B Radic, C Mayor-Ruiz, VA Blomen, C Trefzer, RK Kandasamy, ...
Nature chemical biology 10 (9), 768-773, 2014
1752014
Target profiling of an antimetastatic RAPTA agent by chemical proteomics: relevance to the mode of action
MV Babak, SM Meier, KVM Huber, J Reynisson, AA Legin, MA Jakupec, ...
Chemical science 6 (4), 2449-2456, 2015
1552015
Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions
R Martins, J Maier, AD Gorki, KVM Huber, O Sharif, P Starkl, S Saluzzo, ...
Nature immunology 17 (12), 1361-1372, 2016
1322016
Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site
E Hadzijusufovic, K Albrecht-Schgoer, K Huber, G Hoermann, F Grebien, ...
Leukemia 31 (11), 2388-2397, 2017
1312017
Functional role and therapeutic potential of the pim-1 kinase in colon carcinoma
U Weirauch, N Beckmann, M Thomas, A Grünweller, K Huber, F Bracher, ...
Neoplasia 15 (7), 783-IN28, 2013
1122013
A chemical biology toolbox to study protein methyltransferases and epigenetic signaling
S Scheer, S Ackloo, TS Medina, M Schapira, F Li, JA Ward, AM Lewis, ...
Nature communications 10 (1), 19, 2019
1112019
Discovery of a PCAF bromodomain chemical probe
M Moustakim, PGK Clark, L Trulli, AL Fuentes de Arriba, MT Ehebauer, ...
Angewandte Chemie 129 (3), 845-849, 2017
882017
7, 8-Dichloro-1-oxo-β-carbolines as a versatile scaffold for the development of potent and selective kinase inhibitors with unusual binding modes
K Huber, L Brault, O Fedorov, C Gasser, P Filippakopoulos, AN Bullock, ...
Journal of medicinal chemistry 55 (1), 403-413, 2012
832012
Novel 3-Arylideneindolin-2-ones as Inhibitors of NAD+-Dependent Histone Deacetylases (Sirtuins)
K Huber, J Schemies, U Uciechowska, JM Wagner, T Rumpf, F Lewrick, ...
Journal of medicinal chemistry 53 (3), 1383-1386, 2010
822010
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