Masayuki Nagahashi
Masayuki Nagahashi
Hyogo College of Medicine
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Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer
J Liang, M Nagahashi, EY Kim, KB Harikumar, A Yamada, WC Huang, ...
Cancer cell 23 (1), 107-120, 2013
Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis
M Nagahashi, S Ramachandran, EY Kim, JC Allegood, OM Rashid, ...
Cancer research 72 (3), 726-735, 2012
Conjugated bile acids activate the sphingosine‐1‐phosphate receptor 2 in primary rodent hepatocytes
E Studer, X Zhou, R Zhao, Y Wang, K Takabe, M Nagahashi, WM Pandak, ...
Hepatology 55 (1), 267-276, 2012
Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2
K Takabe, RH Kim, JC Allegood, P Mitra, S Ramachandran, M Nagahashi, ...
Journal of Biological Chemistry 285 (14), 10477-10486, 2010
p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming
T Saito, Y Ichimura, K Taguchi, T Suzuki, T Mizushima, K Takagi, Y Hirose, ...
Nature communications 7 (1), 12030, 2016
Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression
M Nagahashi, K Takabe, R Liu, K Peng, X Wang, Y Wang, NC Hait, ...
Hepatology 61 (4), 1216-1226, 2015
Targeting the SphK1/S1P/S1PR1 axis that links obesity, chronic inflammation, and breast cancer metastasis
M Nagahashi, A Yamada, E Katsuta, T Aoyagi, WC Huang, KP Terracina, ...
Cancer research 78 (7), 1713-1725, 2018
The role of sphingosine 1‐phosphate receptor 2 in bile‐acid–induced cholangiocyte proliferation and cholestasis‐induced liver injury in mice
Y Wang, H Aoki, J Yang, K Peng, R Liu, X Li, X Qiang, L Sun, EC Gurley, ...
Hepatology 65 (6), 2005-2018, 2017
Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network
M Nagahashi, EY Kim, A Yamada, S Ramachandran, JC Allegood, ...
The FASEB Journal 27 (3), 1001, 2013
Next generation sequencing‐based gene panel tests for the management of solid tumors
M Nagahashi, Y Shimada, H Ichikawa, H Kameyama, K Takabe, S Okuda, ...
Cancer science 110 (1), 6-15, 2019
Preoperative predictors of vascular invasion in hepatocellular carcinoma
J Sakata, Y Shirai, T Wakai, K Kaneko, M Nagahashi, K Hatakeyama
European Journal of Surgical Oncology (EJSO) 34 (8), 900-905, 2008
Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer
K Moro, M Nagahashi, R Ramanathan, K Takabe, T Wakai
World journal of clinical cases 4 (7), 155, 2016
Is tail vein injection a relevant breast cancer lung metastasis model?
OM Rashid, M Nagahashi, S Ramachandran, CI Dumur, JC Schaum, ...
Journal of thoracic disease 5 (4), 385, 2013
Sphingosine‐1‐phosphate transporters as targets for cancer therapy
M Nagahashi, K Takabe, KP Terracina, D Soma, Y Hirose, T Kobayashi, ...
BioMed research international 2014 (1), 651727, 2014
Resection of the primary tumor improves survival in metastatic breast cancer by reducing overall tumor burden
OM Rashid, M Nagahashi, S Ramachandran, L Graham, A Yamada, ...
Surgery 153 (6), 771-778, 2013
The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer
NC Hait, D Avni, A Yamada, M Nagahashi, T Aoyagi, H Aoki, CI Dumur, ...
Oncogenesis 4 (6), e156-e156, 2015
The role of sphingosine‐1‐phosphate in inflammation and cancer progression
M Nagahashi, M Abe, K Sakimura, K Takabe, T Wakai
Cancer science 109 (12), 3671-3678, 2018
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases
M Nagahashi, K Yuza, Y Hirose, M Nakajima, R Ramanathan, NC Hait, ...
Journal of lipid research 57 (9), 1636-1643, 2016
The E2F pathway score as a predictive biomarker of response to neoadjuvant therapy in ER+/HER2− breast cancer
M Oshi, H Takahashi, Y Tokumaru, L Yan, OM Rashid, M Nagahashi, ...
Cells 9 (7), 1643, 2020
High levels of sphingolipids in human breast cancer
M Nagahashi, J Tsuchida, K Moro, M Hasegawa, K Tatsuda, IA Woelfel, ...
journal of surgical research 204 (2), 435-444, 2016
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