Metabolite profiling and integrative modeling reveal metabolic constraints for carbon partitioning under nitrogen starvation in the green algae Haematococcus pluvialis L Recht, N Töpfer, A Batushansky, N Sikron, Y Gibon, A Fait, Z Nikoloski, ... Journal of Biological Chemistry 289 (44), 30387-30403, 2014 | 120 | 2014 |
Integration of metabolomics data into metabolic networks N Töpfer, S Kleessen, Z Nikoloski Frontiers in plant science 6, 49, 2015 | 106 | 2015 |
The PhytoClust tool for metabolic gene clusters discovery in plant genomes N Töpfer, LM Fuchs, A Aharoni Nucleic Acids Research 45 (12), 7049-7063, 2017 | 96 | 2017 |
Label‐free deep shotgun proteomics reveals protein dynamics during tomato fruit tissues development J Szymanski, Y Levin, A Savidor, D Breitel, L Chappell‐Maor, U Heinig, ... The Plant Journal 90 (2), 396-417, 2017 | 71 | 2017 |
Integration of genome-scale modeling and transcript profiling reveals metabolic pathways underlying light and temperature acclimation in Arabidopsis N Töpfer, C Caldana, S Grimbs, L Willmitzer, AR Fernie, Z Nikoloski The Plant Cell 25 (4), 1197-1211, 2013 | 51 | 2013 |
Alternative Crassulacean Acid Metabolism Modes Provide Environment-Specific Water-Saving Benefits in a Leaf Metabolic Model N Töpfer, T Braam, S Shameer, RG Ratcliffe, LJ Sweetlove The Plant Cell 32 (12), 3689-3705, 2020 | 50 | 2020 |
iReMet-flux: constraint-based approach for integrating relative metabolite levels into a stoichiometric metabolic models M Sajitz-Hermstein, N Töpfer, S Kleessen, AR Fernie, Z Nikoloski Bioinformatics 32 (17), i755-i762, 2016 | 34 | 2016 |
Advances in Flux Balance Analysis by Integrating Machine Learning and Mechanism-based Models A Sahu, MA Blätke, JJ Szymañski, N Töpfer Computational and Structural Biotechnology Journal, 2021 | 32 | 2021 |
Integration of time-resolved transcriptomics data with flux-based methods reveals stress-induced metabolic adaptation in Escherichia coli N Töpfer, S Jozefczuk, Z Nikoloski BMC Systems Biology 6 (1), 1-10, 2012 | 30 | 2012 |
Variability of metabolite levels is linked to differential metabolic pathways in Arabidopsis's responses to abiotic stresses N Töpfer, F Scossa, A Fernie, Z Nikoloski PLoS Comput Biol 10 (6), e1003656, 2014 | 20 | 2014 |
Integration of Plant Metabolomics Data with Metabolic Networks: Progresses and Challenges N Töpfer, SMD Seaver, A Aharoni Plant Metabolomics, 297-310, 2018 | 16 | 2018 |
Environment-coupled models of leaf metabolism N Töpfer Biochemical Society Transactions 49 (1), 119-129, 2021 | 8 | 2021 |
Large-scale modeling provides insights into Arabidopsis's acclimation to changing light and temperature conditions N Töpfer, Z Niokoloski Plant signaling & behavior 8 (9), 1197-211, 2013 | 7 | 2013 |
CobraMod: A pathway-centric curation tool for constraint-based metabolic models S Camborda, JN Weder, N Töpfer Bioinformatics, 2022 | 4 | 2022 |
CAM emerges in a leaf metabolic model under water-saving constraints in different environments N Töpfer, T Braam, S Shameer, RG Ratcliffe, LJ Sweetlove bioRxiv, 2020 | 2 | 2020 |
Proteome reorganization and amino acid metabolism during germination and seedling establishment in Lupinus albus C Angermann, B Heinemann, J Hansen, N Töpfer, HP Braun, ... Journal of Experimental Botany, erae197, 2024 | | 2024 |
Towards Multiscale Modeling to Predict Diatom Metabolites Production for Biofuels and High-Value Compounds M Branco-Vieira, NS Caetano, ARJ Lima, N Töpfer International Conference on Energy and Environment Research, 325-337, 2023 | | 2023 |
Optimization-based Approaches for Analyzing Metabolic Adjustment to Changing Environmental Conditions N Töpfer | | 2014 |