Javier Perales-Patón
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Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic TransformationMutant CALR Requires Its C-terminus and MPL to Transform
S Elf, NS Abdelfattah, E Chen, J Perales-Patón, EA Rosen, A Ko, ...
Cancer discovery 6 (4), 368-381, 2016
Decoding myofibroblast origins in human kidney fibrosis
C Kuppe, MM Ibrahim, J Kranz, X Zhang, S Ziegler, J Perales-Patón, ...
Nature 589 (7841), 281-286, 2021
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ...
Genome biology 21, 1-19, 2020
The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during CarcinogenesismiR-146b-3p Inhibits Iodide Uptake in …
G Riesco-Eizaguirre, L Wert-Lamas, J Perales-Paton, A Sastre-Perona, ...
Cancer research 75 (19), 4119-4130, 2015
Functional screen of MSI2 interactors identifies an essential role for SYNCRIP in myeloid leukemia stem cells
LP Vu, C Prieto, EM Amin, S Chhangawala, A Krivtsov, MN Calvo-Vidal, ...
Nature genetics 49 (6), 866-875, 2017
Complete regression of advanced pancreatic ductal adenocarcinomas upon combined inhibition of EGFR and C-RAF
MT Blasco, C Navas, G Martín-Serrano, O Grana-Castro, CG Lechuga, ...
Cancer cell 35 (4), 573-587. e6, 2019
PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data
E Piñeiro-Yáñez, M Reboiro-Jato, G Gómez-López, J Perales-Patón, ...
Genome medicine 10, 1-11, 2018
MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors
V Mancikova, E Castelblanco, E Pineiro-Yanez, J Perales-Paton, ...
Modern Pathology 28 (6), 748-757, 2015
Differential expression of microRNA miR-150-5p in IgA nephropathy as a potential mediator and marker of disease progression
IZA Pawluczyk, A Didangelos, SJ Barbour, L Er, JU Becker, R Martin, ...
Kidney international 99 (5), 1127-1139, 2021
Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in RETM918T TumorsGenomic Integration in Medullary Thyroid …
V Mancikova, C Montero-Conde, J Perales-Paton, A Fernandez, ...
Clinical Cancer Research 23 (5), 1334-1345, 2017
Discovery of New Targets to Control Metastasis in Pancreatic Cancer by Single-cell Transcriptomics Analysis of Circulating Tumor CellsSingle-cell RNA-seq to Uncover Metastatic …
S Dimitrov-Markov, J Perales-Patón, B Bockorny, A Dopazo, M Muñoz, ...
Molecular Cancer Therapeutics 19 (8), 1751-1760, 2020
Pancreas cancer precision treatment using avatar mice from a bioinformatics perspective
J Perales-Patón, E Piñeiro-Yañez, H Tejero, PP López-Casas, M Hidalgo, ...
Public health genomics 20 (2), 81-91, 2017
Clonal dynamics monitoring during clinical evolution in chronic lymphocytic leukaemia
J González-Rincón, S Gómez, N Martinez, K Troulé, J Perales-Patón, ...
Scientific Reports 9 (1), 975, 2019
Experimental and computational technologies to dissect the kidney at the single-cell level
C Kuppe, J Perales-Patón, J Saez-Rodriguez, R Kramann
Nephrology Dialysis Transplantation 37 (4), 628-637, 2022
vulcanSpot: a tool to prioritize therapeutic vulnerabilities in cancer
J Perales-Patón, T Di Domenico, C Fustero-Torre, E Piñeiro-Yáñez, ...
Bioinformatics 35 (22), 4846-4848, 2019
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling
K van Kuijk, JAF Demandt, J Perales-Patón, TL Theelen, C Kuppe, ...
Cardiovascular Research 118 (5), 1232-1246, 2022
Dianhydrogalactitol Overcomes Multiple Temozolomide Resistance Mechanisms in GlioblastomaDianhydrogalactitol Bypasses TMZ Resistance
M Jiménez-Alcázar, Á Curiel-García, P Nogales, J Perales-Patón, ...
Molecular cancer therapeutics 20 (6), 1029-1038, 2021
Physical interaction between mutant calreticulin and the thrombopoietin receptor is required for hematopoietic transformation
S Elf, N Abdelfattah, E Chen, J Perales-Patón, E Rosen, A Ko, F Peisker, ...
Blood 126 (23), LBA-4, 2015
Partial inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2, 6-Bisphosphatase-3 (PFKFB3) enzyme in myeloid cells does not affect atherosclerosis
RJHA Tillie, J De Bruijn, J Perales-Patón, L Temmerman, Y Ghosheh, ...
Frontiers in Cell and Developmental Biology 9, 695684, 2021
Cross-regional homeostatic and reactive glial signatures in multiple sclerosis
T Trobisch, A Zulji, NA Stevens, S Schwarz, S Wischnewski, M Öztürk, ...
Acta Neuropathologica 144 (5), 987-1003, 2022
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