Fran Supek

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Tomislav ŠmucSenior scientist, Rudjer Boskovic Institute, Zagreb, CroatiaVerified email at irb.hr
Ben LehnerHuman Genetics, Wellcome Sanger Institute; Systems and Synthetic Biology, CRGVerified email at crg.eu
Nives SkuncaPostdoctoral Fellow, ETH ZürichVerified email at inf.ethz.ch
Matko BošnjakDeepMindVerified email at deepmind.com
Anita KriskoUniversity Medical Center Goettingen, Department of Experimental NeurodegenerationVerified email at med.uni-goettingen.de
Toni GabaldonGroup Leader, Institute for Research in Biomedicine (IRB) and Barcelona Supercomputing Centre (BSC)Verified email at crg.es
Rik GH LindeboomWellcome Sanger Institute, Cambridge, United KingdomVerified email at sanger.ac.uk
Marina SalvadoresIRB BarcelonaVerified email at irbbarcelona.org
Jurica LevaticPostdoc, Department of Knowledge Technologies, Jožef Stefan Institute, Ljubljana, SloveniaVerified email at ijs.si
Marko MarjanovicRudjer Boskovic InstituteVerified email at irb.hr
David Mas-PontePhD Student, IRB, BarcelonaVerified email at irbbarcelona.org
Tobias WarneckeMRC London Institute of Medical Sciences (LMS) & Imperial College LondonVerified email at lms.mrc.ac.uk
Belen MiñanaCenter for Genomic RegulationVerified email at crg.es
Juan ValcarcelICREA Research Professor, Center for Genomic RegulationVerified email at crg.eu
Vedrana VidulinPink Data AnalyticsVerified email at pinkdataanalytics.com
Saso DzeroskiJozef Stefan Institute, Dept. of Knowledge TechnologiesVerified email at ijs.si
Solip ParkCentre for Genomic RegulationVerified email at crg.eu
Maria BrbićEPFLVerified email at cs.stanford.edu
Jelena ReparResearch associate at Ruder Boskovic Institute, CroatiaVerified email at irb.hr
Insuk LeeYonsei UniversityVerified email at yonsei.ac.kr

Fran Supek

Genome Data Science (group leader), IRB Barcelona; ICREA Research Professor

Verified email at irb.hr - Homepage

Human Genomics Somatic Mutations Gene Function Phenomics Data Science


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REVIGO summarizes and visualizes long lists of gene ontology terms F Supek, M Bošnjak, N Škunca, T Šmuc PloS one 6 (7), e21800, 2011	4918	2011
A large-scale evaluation of computational protein function prediction P Radivojac, WT Clark, TR Oron, AM Schnoes, T Wittkop, A Sokolov, ... Nature methods 10 (3), 221-227, 2013	909	2013
Synonymous mutations frequently act as driver mutations in human cancers F Supek, B Miñana, J Valcárcel, T Gabaldón, B Lehner Cell 156 (6), 1324-1335, 2014	533	2014
An expanded evaluation of protein function prediction methods shows an improvement in accuracy Y Jiang, TR Oron, WT Clark, AR Bankapur, D D’Andrea, R Lepore, ... Genome biology 17 (1), 1-19, 2016	356	2016
Differential DNA mismatch repair underlies mutation rate variation across the human genome F Supek, B Lehner Nature 521 (7550), 81-84, 2015	353	2015
The rules and impact of nonsense-mediated mRNA decay in human cancers RGH Lindeboom, F Supek, B Lehner Nature genetics 48 (10), 1112-1118, 2016	333	2016
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens N Zhou, Y Jiang, TR Bergquist, AJ Lee, BZ Kacsoh, AW Crocker, ... Genome biology 20 (1), 1-23, 2019	245	2019
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ... Nature genetics 52 (3), 306-319, 2020	228	2020
Clustered Mutation Signatures Reveal that Error-Prone DNA Repair Targets Mutations to Active Genes F Supek, B Lehner Cell 130 (3), 534-547, 2017	163	2017
Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity F Supek, K Vlahoviček BMC bioinformatics 6, 1-15, 2005	145	2005
MUFFINN: cancer gene discovery via network analysis of somatic mutation data A Cho, JE Shim, E Kim, F Supek, B Lehner, I Lee Genome biology 17 (1), 1-16, 2016	128	2016
The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy RGH Lindeboom, M Vermeulen, B Lehner, F Supek Nature genetics 51 (11), 1645-1651, 2019	123	2019
INCA: synonymous codon usage analysis and clustering by means of self-organizing map F Supek, K Vlahoviček Bioinformatics 20 (14), 2329-2330, 2004	123	2004
Translational selection is ubiquitous in prokaryotes F Supek, N Škunca, J Repar, K Vlahoviček, T Šmuc PLoS genetics 6 (6), e1001004, 2010	87	2010
On Relevance of Codon Usage to Expression of Synthetic and Natural Genes in Escherichia coli F Supek, T \# 352; muc Genetics 185 (3), 1129-1134, 2010	85	2010
The landscape of microbial phenotypic traits and associated genes M Brbić, M Piškorec, V Vidulin, A Kriško, T Šmuc, F Supek Nucleic acids research, gkw964, 2016	84	2016
Antitumor potential of crown ethers: structure− activity relationships, cell cycle disturbances, and cell death studies of a series of ionophores M Marjanović, M Kralj, F Supek, L Frkanec, I Piantanida, T Šmuc, ... Journal of medicinal chemistry 50 (5), 1007-1018, 2007	71	2007
To NMD or not to NMD: nonsense-mediated mRNA decay in cancer and other genetic diseases F Supek, B Lehner, RGH Lindeboom Trends in genetics 37 (7), 657-668, 2021	66	2021
The code of silence: widespread associations between synonymous codon biases and gene function F Supek Journal of molecular evolution 82, 65-73, 2016	60	2016
Accurate models for P-gp drug recognition induced from a cancer cell line cytotoxicity screen J Levatic, J Curak, M Kralj, T Smuc, M Osmak, F Supek Journal of medicinal chemistry 56 (14), 5691-5708, 2013	58	2013

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