Dying and necrotic neutrophils are anti-inflammatory secondary to the release of α-defensins K Miles, DJ Clarke, W Lu, Z Sibinska, PE Beaumont, DJ Davidson, ... The Journal of Immunology 183 (3), 2122-2132, 2009 | 197 | 2009 |
Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex D Wallock-Richards, CJ Doherty, L Doherty, DJ Clarke, M Place, ... PLoS One 9 (12), e112726, 2014 | 173 | 2014 |
The chemical basis of serine palmitoyltransferase inhibition by myriocin JM Wadsworth, DJ Clarke, SA McMahon, JP Lowther, AE Beattie, ... Journal of the American Chemical Society 135 (38), 14276-14285, 2013 | 148 | 2013 |
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity ML Choi, A Chappard, BP Singh, C Maclachlan, M Rodrigues, ... Nature neuroscience 25 (9), 1134-1148, 2022 | 141 | 2022 |
Analysis and separation of residues important for the chemoattractant and antimicrobial activities of β-defensin 3 K Taylor, DJ Clarke, B McCullough, W Chin, E Seo, D Yang, J Oppenheim, ... Journal of Biological Chemistry 283 (11), 6631-6639, 2008 | 122 | 2008 |
Structure-activity relationships in defensin dimers: a novel link between β-defensin tertiary structure and antimicrobial activity DJ Campopiano, DJ Clarke, NC Polfer, PE Barran, RJ Langley, ... Journal of Biological Chemistry 279 (47), 48671-48679, 2004 | 120 | 2004 |
Interlaboratory study for characterizing monoclonal antibodies by top-down and middle-down mass spectrometry K Srzentic, L Fornelli, YO Tsybin, JA Loo, H Seckler, JN Agar, ... Journal of the American Society for Mass Spectrometry 31 (9), 1783-1802, 2020 | 106 | 2020 |
Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments. D He, S Hughes, S Vanden-Hehir, A Georgiev, K Altenbach, E Tarrant, ... eLife 5, e18972, 2016 | 97 | 2016 |
Chemical diversity and complexity of scotch whisky as revealed by high-resolution mass spectrometry W Kew, I Goodall, D Clarke, D Uhrín Journal of the American Society for Mass Spectrometry 28 (1), 200-213, 2016 | 94 | 2016 |
S-nitrosylation of the zinc finger protein SRG1 regulates plant immunity B Cui, Q Pan, D Clarke, MO Villarreal, S Umbreen, B Yuan, W Shan, ... Nature Communications 9 (1), 4226, 2018 | 88 | 2018 |
Is it biologically relevant to measure the structures of small peptides in the gas-phase? PE Barran, NC Polfer, DJ Campopiano, DJ Clarke, PRR Langridge-Smith, ... International Journal of Mass Spectrometry 240 (3), 273-284, 2005 | 79 | 2005 |
Interactive van Krevelen diagrams – Advanced visualisation of mass spectrometry data of complex mixtures. W Kew, J Blackburn, D Clarke, D Uhrin Rapid Comms. Mass. Spec. 31 (7), 658–662, 2017 | 74 | 2017 |
Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone DJ Wallock-Richards, J Marles-Wright, DJ Clarke, A Maitra, M Dodds, ... Chemical communications 51 (52), 10483-10485, 2015 | 69 | 2015 |
Maturation of McjA precursor peptide into active microcin MccJ25 DJ Clarke, DJ Campopiano Organic & biomolecular chemistry 5 (16), 2564-2566, 2007 | 63 | 2007 |
Cellular redox potential and the biomolecular electrochemical series: A systems hypothesis V Mallikarjun, DJ Clarke, CJ Campbell Free Radical Biology and Medicine 53 (2), 280-288, 2012 | 61 | 2012 |
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation J Lowther, BA Yard, KA Johnson, LG Carter, VT Bhat, MCC Raman, ... Molecular BioSystems 6 (9), 1682-1693, 2010 | 60 | 2010 |
IL-1β–induced protection of keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2 B Wang, BJ McHugh, A Qureshi, DJ Campopiano, DJ Clarke, ... Journal of Investigative Dermatology 137 (1), 95-105, 2017 | 59 | 2017 |
Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry J Scotcher, DJ Clarke, SK Weidt, CL Mackay, TR Hupp, PJ Sadler, ... Journal of the American Society for Mass Spectrometry 22 (5), 888-897, 2011 | 58 | 2011 |
Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution DJ Clarke, DJ Campopiano Analyst 140 (8), 2679-2686, 2015 | 55 | 2015 |
Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity CM Tron, IW McNae, M Nutley, DJ Clarke, A Cooper, MD Walkinshaw, ... Journal of molecular biology 387 (1), 129-146, 2009 | 54 | 2009 |