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David J. Clarke
David J. Clarke
Professor of Mass Spectrometry, School of Chemistry. University of Edinburgh
Verified email at ed.ac.uk - Homepage
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Cited by
Cited by
Year
Dying and necrotic neutrophils are anti-inflammatory secondary to the release of α-defensins
K Miles, DJ Clarke, W Lu, Z Sibinska, PE Beaumont, DJ Davidson, ...
The Journal of Immunology 183 (3), 2122-2132, 2009
1972009
Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex
D Wallock-Richards, CJ Doherty, L Doherty, DJ Clarke, M Place, ...
PLoS One 9 (12), e112726, 2014
1732014
The chemical basis of serine palmitoyltransferase inhibition by myriocin
JM Wadsworth, DJ Clarke, SA McMahon, JP Lowther, AE Beattie, ...
Journal of the American Chemical Society 135 (38), 14276-14285, 2013
1482013
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity
ML Choi, A Chappard, BP Singh, C Maclachlan, M Rodrigues, ...
Nature neuroscience 25 (9), 1134-1148, 2022
1412022
Analysis and separation of residues important for the chemoattractant and antimicrobial activities of β-defensin 3
K Taylor, DJ Clarke, B McCullough, W Chin, E Seo, D Yang, J Oppenheim, ...
Journal of Biological Chemistry 283 (11), 6631-6639, 2008
1222008
Structure-activity relationships in defensin dimers: a novel link between β-defensin tertiary structure and antimicrobial activity
DJ Campopiano, DJ Clarke, NC Polfer, PE Barran, RJ Langley, ...
Journal of Biological Chemistry 279 (47), 48671-48679, 2004
1202004
Interlaboratory study for characterizing monoclonal antibodies by top-down and middle-down mass spectrometry
K Srzentic, L Fornelli, YO Tsybin, JA Loo, H Seckler, JN Agar, ...
Journal of the American Society for Mass Spectrometry 31 (9), 1783-1802, 2020
1062020
Structural characterization of encapsulated ferritin provides insight into iron storage in bacterial nanocompartments.
D He, S Hughes, S Vanden-Hehir, A Georgiev, K Altenbach, E Tarrant, ...
eLife 5, e18972, 2016
972016
Chemical diversity and complexity of scotch whisky as revealed by high-resolution mass spectrometry
W Kew, I Goodall, D Clarke, D Uhrín
Journal of the American Society for Mass Spectrometry 28 (1), 200-213, 2016
942016
S-nitrosylation of the zinc finger protein SRG1 regulates plant immunity
B Cui, Q Pan, D Clarke, MO Villarreal, S Umbreen, B Yuan, W Shan, ...
Nature Communications 9 (1), 4226, 2018
882018
Is it biologically relevant to measure the structures of small peptides in the gas-phase?
PE Barran, NC Polfer, DJ Campopiano, DJ Clarke, PRR Langridge-Smith, ...
International Journal of Mass Spectrometry 240 (3), 273-284, 2005
792005
Interactive van Krevelen diagrams – Advanced visualisation of mass spectrometry data of complex mixtures.
W Kew, J Blackburn, D Clarke, D Uhrin
Rapid Comms. Mass. Spec. 31 (7), 658–662, 2017
742017
Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone
DJ Wallock-Richards, J Marles-Wright, DJ Clarke, A Maitra, M Dodds, ...
Chemical communications 51 (52), 10483-10485, 2015
692015
Maturation of McjA precursor peptide into active microcin MccJ25
DJ Clarke, DJ Campopiano
Organic & biomolecular chemistry 5 (16), 2564-2566, 2007
632007
Cellular redox potential and the biomolecular electrochemical series: A systems hypothesis
V Mallikarjun, DJ Clarke, CJ Campbell
Free Radical Biology and Medicine 53 (2), 280-288, 2012
612012
Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation
J Lowther, BA Yard, KA Johnson, LG Carter, VT Bhat, MCC Raman, ...
Molecular BioSystems 6 (9), 1682-1693, 2010
602010
IL-1β–induced protection of keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2
B Wang, BJ McHugh, A Qureshi, DJ Campopiano, DJ Clarke, ...
Journal of Investigative Dermatology 137 (1), 95-105, 2017
592017
Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry
J Scotcher, DJ Clarke, SK Weidt, CL Mackay, TR Hupp, PJ Sadler, ...
Journal of the American Society for Mass Spectrometry 22 (5), 888-897, 2011
582011
Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution
DJ Clarke, DJ Campopiano
Analyst 140 (8), 2679-2686, 2015
552015
Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity
CM Tron, IW McNae, M Nutley, DJ Clarke, A Cooper, MD Walkinshaw, ...
Journal of molecular biology 387 (1), 129-146, 2009
542009
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