Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study H Yu, L Lin, Z Zhang, H Zhang, H Hu Signal transduction and targeted therapy 5 (1), 209, 2020 | 1279 | 2020 |
Ubiquitin signaling in immune responses H Hu, SC Sun Cell research 26 (4), 457-483, 2016 | 466 | 2016 |
NF‐κB signaling in inflammation and cancer T Zhang, C Ma, Z Zhang, H Zhang, H Hu MedComm 2 (4), 618-653, 2021 | 286 | 2021 |
Pan-cancer single-cell analysis reveals the heterogeneity and plasticity of cancer-associated fibroblasts in the tumor microenvironment H Luo, X Xia, LB Huang, H An, M Cao, GD Kim, HN Chen, WH Zhang, ... Nature communications 13 (1), 6619, 2022 | 248 | 2022 |
USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses Q Zou, J Jin, H Hu, HS Li, S Romano, Y Xiao, M Nakaya, X Zhou, X Cheng, ... Nature immunology 15 (6), 562-570, 2014 | 243 | 2014 |
OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3 H Hu, GC Brittain, JH Chang, N Puebla-Osorio, J Jin, A Zal, Y Xiao, ... Nature 494 (7437), 371-374, 2013 | 215 | 2013 |
Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation Y Xiao, J Jin, M Chang, JH Chang, H Hu, X Zhou, GC Brittain, ... Nature medicine 19 (5), 595-602, 2013 | 203 | 2013 |
Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity J Jin, H Hu, HS Li, J Yu, Y Xiao, GC Brittain, Q Zou, X Cheng, FA Mallette, ... Immunity 40 (3), 342-354, 2014 | 158 | 2014 |
The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-κB signaling J Jin, Y Xiao, JH Chang, J Yu, H Hu, R Starr, GC Brittain, M Chang, ... Nature immunology 13 (11), 1101-1109, 2012 | 151 | 2012 |
Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells JH Chang, Y Xiao, H Hu, J Jin, J Yu, X Zhou, X Wu, HM Johnson, S Akira, ... Nature immunology 13 (5), 481-490, 2012 | 138 | 2012 |
Single-cell RNA sequencing resolves spatiotemporal development of pre-thymic lymphoid progenitors and thymus organogenesis in human embryos Y Zeng, C Liu, Y Gong, Z Bai, S Hou, J He, Z Bian, Z Li, Y Ni, J Yan, ... Immunity 51 (5), 930-948. e6, 2019 | 120 | 2019 |
Epigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid. SSC Jin J, Xie X, Xiao Y, Hu H, Zou Q, Cheng X Nature Immunology 17 (3), 259-68, 2016 | 118 | 2016 |
TRIM29 negatively controls antiviral immune response through targeting STING for degradation Q Li, L Lin, Y Tong, Y Liu, J Mou, X Wang, X Wang, Y Gong, Y Zhao, Y Liu, ... Cell discovery 4 (1), 13, 2018 | 112 | 2018 |
Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. SSC Hu H, Wang H, Xiao Y, Jin J, Chang JH, Zou Q, Xie X, Cheng X J Exp Med 213 (3), 399-414, 2016 | 106 | 2016 |
Noncanonical NF-κB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development H Hu, X Wu, W Jin, M Chang, X Cheng, SC Sun Proceedings of the National Academy of Sciences 108 (31), 12827-12832, 2011 | 105 | 2011 |
Ferroptosis promotes T-cell activation-induced neurodegeneration in multiple sclerosis J Luoqian, W Yang, X Ding, Q Tuo, Z Xiang, Z Zheng, Y Guo, L Li, P Guan, ... Cellular & molecular immunology 19 (8), 913-924, 2022 | 103 | 2022 |
Characterizing dedifferentiation of thyroid cancer by integrated analysis H Luo, X Xia, GD Kim, Y Liu, Z Xue, L Zhang, Y Shu, T Yang, Y Chen, ... Science Advances 7 (31), eabf3657, 2021 | 102 | 2021 |
Self-dsDNA in the pathogenesis of systemic lupus erythematosus Y Bai, Y Tong, Y Liu, H Hu Clinical & Experimental Immunology 191 (1), 1-10, 2018 | 100 | 2018 |
Response of memory CD8+ T cells to severe acute respiratory syndrome (SARS) coronavirus in recovered SARS patients and healthy individuals H Chen, J Hou, X Jiang, S Ma, M Meng, B Wang, M Zhang, M Zhang, ... The Journal of Immunology 175 (1), 591-598, 2005 | 96 | 2005 |
Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages J Jin, Y Xiao, H Hu, Q Zou, Y Li, Y Gao, W Ge, X Cheng, SC Sun Nature communications 6 (1), 5930, 2015 | 95 | 2015 |