| Natural history of β-cell adaptation and failure in type 2 diabetes EU Alejandro, B Gregg, M Blandino-Rosano, C Cras-Méneur, ... Molecular aspects of medicine 42, 19-41, 2015 | 262 | 2015 |
| Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome JD Johnson, E Bernal-Mizrachi, EU Alejandro, Z Han, TB Kalynyak, H Li, ... Proceedings of the National Academy of Sciences 103 (51), 19575-19580, 2006 | 234 | 2006 |
| Gestational diabetes mellitus: a harbinger of the vicious cycle of diabetes EU Alejandro, TP Mamerto, G Chung, A Villavieja, NL Gaus, E Morgan, ... International journal of molecular sciences 21 (14), 5003, 2020 | 215 | 2020 |
| Carboxypeptidase E mediates palmitate-induced β-cell ER stress and apoptosis KD Jeffrey, EU Alejandro, DS Luciani, TB Kalynyak, X Hu, H Li, Y Lin, ... Proceedings of the National Academy of Sciences 105 (24), 8452-8457, 2008 | 185 | 2008 |
| Insulin stimulates primary β-cell proliferation via Raf-1 kinase JL Beith, EU Alejandro, JD Johnson Endocrinology 149 (5), 2251-2260, 2008 | 136 | 2008 |
| Granulin‐epithelin precursor is a novel prognostic marker in epithelial ovarian carcinoma B Davidson, E Alejandro, VA Flørenes, JM Goderstad, B Risberg, ... Cancer: Interdisciplinary International Journal of the American Cancer …, 2004 | 115 | 2004 |
| Maternal diet–induced microRNAs and mTOR underlie β cell dysfunction in offspring EU Alejandro, B Gregg, T Wallen, D Kumusoglu, D Meister, A Chen, ... The Journal of clinical investigation 124 (10), 4395-4410, 2014 | 109 | 2014 |
| mTORC1 signaling and regulation of pancreatic β-cell mass M Blandino-Rosano, AY Chen, JO Scheys, EU Alejandro, AP Gould, ... Cell Cycle 11 (10), 1892-1902, 2012 | 98 | 2012 |
| Lysophosphatidic acid and endothelin-induced proliferation of ovarian cancer cell lines is mitigated by neutralization of granulin–epithelin precursor (GEP), a prosurvival … M Kamrava, F Simpkins, E Alejandro, C Michener, E Meltzer, EC Kohn Oncogene 24 (47), 7084-7093, 2005 | 88 | 2005 |
| Lysophosphatidic acid and endothelin-induced proliferation of ovarian cancer cell lines is mitigated by neutralization of granulin–epithelin precursor (GEP), a prosurvival … M Kamrava, F Simpkins, E Alejandro, C Michener, E Meltzer, EC Kohn Oncogene 24 (47), 7084-7093, 2005 | 88 | 2005 |
| Inhibition of Raf-1 alters multiple downstream pathways to induce pancreatic β-cell apoptosis EU Alejandro, JD Johnson Journal of Biological Chemistry 283 (4), 2407-2417, 2008 | 73 | 2008 |
| Disruption of O-linked N-acetylglucosamine signaling induces ER stress and β cell failure EU Alejandro, N Bozadjieva, D Kumusoglu, S Abdulhamid, H Levine, ... Cell reports 13 (11), 2527-2538, 2015 | 68 | 2015 |
| Nutrient sensor signaling pathways and cellular stress in fetal growth restriction B Hart, E Morgan, EU Alejandro Journal of molecular endocrinology 62 (2), R155-R165, 2019 | 58 | 2019 |
| Role of nutrients and mTOR signaling in the regulation of pancreatic progenitors development L Elghazi, M Blandino-Rosano, E Alejandro, C Cras-Méneur, ... Molecular metabolism 6 (6), 560-573, 2017 | 52 | 2017 |
| Acute insulin signaling in pancreatic beta-cells is mediated by multiple Raf-1 dependent pathways EU Alejandro, TB Kalynyak, F Taghizadeh, KS Gwiazda, EK Rawstron, ... Endocrinology 151 (2), 502-512, 2010 | 52 | 2010 |
| The alarm anti-protease, secretory leukocyte protease inhibitor, is a proliferation and survival factor for ovarian cancer cells FA Simpkins, NM Devoogdt, N Rasool, NE Tchabo, EU Alejandro, ... Carcinogenesis 29 (3), 466-472, 2008 | 51 | 2008 |
| Overexpression of kinase-dead mTOR impairs glucose homeostasis by regulating insulin secretion and not β-cell mass EU Alejandro, N Bozadjieva, M Blandino-Rosano, MA Wasan, L Elghazi, ... Diabetes 66 (8), 2150-2162, 2017 | 47 | 2017 |
| Control of pancreatic β-cell fate by insulin signaling: The sweet spot hypothesis JD Johnson, EU Alejandro Cell Cycle 7 (10), 1343-1347, 2008 | 45 | 2008 |
| Effects of insulin on human pancreatic cancer progression modeled in vitro MT Chan, GE Lim, S Skovsø, YHC Yang, T Albrecht, EU Alejandro, ... BMC cancer 14, 1-12, 2014 | 44 | 2014 |
| Fetal undernutrition, placental insufficiency, and pancreatic β-cell development programming in utero R Mohan, D Baumann, EU Alejandro American Journal of Physiology-Regulatory, Integrative and Comparative …, 2018 | 39 | 2018 |
