| A survey of current trends in computational drug repositioning J Li, S Zheng, B Chen, AJ Butte, SJ Swamidass, Z Lu Briefings in bioinformatics 17 (1), 2-12, 2016 | 563 | 2016 |
| Chem2Bio2RDF: a semantic framework for linking and data mining chemogenomic and systems chemical biology data B Chen, X Dong, D Jiao, H Wang, Q Zhu, Y Ding, D Wild BMC bioinformatics 11 (1), 255, 2010 | 272 | 2010 |
| Assessing Drug Target Association using Semantic Linked Data B Chen, Y Ding, DJ Wild PLoS Computational Biology 8 (7), e1002574, 2012 | 197 | 2012 |
| Gaining insight into off-target mediated effects of drug candidates with a comprehensive systems chemical biology analysis J Scheiber, B Chen, M Milik, SCK Sukuru, A Bender, D Mikhailov, ... Journal of chemical information and modeling 49 (2), 308-317, 2009 | 193 | 2009 |
| Reversal of cancer gene expression correlates with drug efficacy and reveals therapeutic targets B Chen, L Ma, H Paik, M Sirota, W Wei, MS Chua, S So, AJ Butte Nature communications 8 (1), 16022, 2017 | 191 | 2017 |
| Leveraging big data to transform target selection and drug discovery B Chen, AJ Butte Clinical Pharmacology & Therapeutics 99 (3), 285-297, 2016 | 189 | 2016 |
| Leveraging big data to transform target selection and drug discovery B Chen, AJ Butte Clinical Pharmacology & Therapeutics 99 (3), 285-297, 2016 | 189 | 2016 |
| PubChem as a source of polypharmacology B Chen, D Wild, R Guha Journal of chemical information and modeling 49 (9), 2044-2055, 2009 | 167 | 2009 |
| The ChEMBL database as linked open data EL Willighagen, A Waagmeester, O Spjuth, P Ansell, AJ Williams, ... Journal of cheminformatics 5, 1-12, 2013 | 152 | 2013 |
| Predicting drug target interactions using meta-path-based semantic network analysis G Fu, Y Ding, A Seal, B Chen, Y Sun, E Bolton BMC bioinformatics 17, 1-10, 2016 | 145 | 2016 |
| Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types K Yu, B Chen, D Aran, J Charalel, C Yau, DM Wolf, LJ Van ‘T Veer, ... Nature communications 10 (1), 3574, 2019 | 140 | 2019 |
| Harnessing big ‘omics’ data and AI for drug discovery in hepatocellular carcinoma B Chen, L Garmire, DF Calvisi, MS Chua, RK Kelley, X Chen Nature Reviews Gastroenterology & Hepatology 17 (4), 238-251, 2020 | 122 | 2020 |
| Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data K Liu, PA Newbury, BS Glicksberg, WZD Zeng, S Paithankar, ... Nature communications 10 (1), 2138, 2019 | 122 | 2019 |
| Comparison of random forest and Pipeline Pilot Naive Bayes in prospective QSAR predictions. B Chen, RP Sheridan, V Hornak, JH Voigt Journal of Chemical Information and Modeling, 2012 | 122 | 2012 |
| A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS M McMahon, A Contreras, M Holm, T Uechi, CM Forester, X Pang, ... Elife 8, e48847, 2019 | 118 | 2019 |
| MoCL: Data-driven Molecular Fingerprint via Knowledge-aware Contrastive Learning from Molecular Graph M Sun, J Xing, H Wang, B Chen, J Zhou Proceedings of the 27th ACM SIGKDD Conference on Knowledge Discovery & Data …, 2021 | 110 | 2021 |
| Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice S Zhang, X Song, D Cao, Z Xu, B Fan, L Che, J Hu, B Chen, M Dong, ... Journal of hepatology 67 (6), 1194-1203, 2017 | 110 | 2017 |
| Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell … B Chen, W Wei, L Ma, B Yang, RM Gill, MS Chua, AJ Butte, S So Gastroenterology 152 (8), 2022-2036, 2017 | 102 | 2017 |
| Relating hepatocellular carcinoma tumor samples and cell lines using gene expression data in translational research B Chen, M Sirota, H Fan-Minogue, D Hadley, AJ Butte BMC medical genomics 8, 1-10, 2015 | 96 | 2015 |
| Experimental and real-world evidence supporting the computational repurposing of bumetanide for APOE4-related Alzheimer’s disease A Taubes, P Nova, KA Zalocusky, I Kosti, M Bicak, MY Zilberter, Y Hao, ... Nature Aging 1 (10), 932-947, 2021 | 85 | 2021 |
Atul J. ButteDirector, Bakar Computational Health Sciences Institute, University of California, San FranciscoVerified email at ucsf.edu
