| Mass spectrometry based tools to investigate protein–ligand interactions for drug discovery KJ Pacholarz, RA Garlish, RJ Taylor, PE Barran Chemical Society Reviews 41 (11), 4335-4355, 2012 | 166 | 2012 |
| Dynamics of Intact Immunoglobulin G Explored by Drift‐Tube Ion‐Mobility Mass Spectrometry and Molecular Modeling KJ Pacholarz, M Porrini, RA Garlish, RJ Burnley, RJ Taylor, AJ Henry, ... Angewandte Chemie International Edition 53 (30), 7765-7769, 2014 | 114 | 2014 |
| A mass-spectrometry-based framework to define the extent of disorder in proteins R Beveridge, S Covill, KJ Pacholarz, JMD Kalapothakis, CE MacPhee, ... Analytical chemistry 86 (22), 10979-10991, 2014 | 113 | 2014 |
| Use of a charge reducing agent to enable intact mass analysis of cysteine-linked antibody-drug-conjugates by native mass spectrometry KJ Pacholarz, PE Barran EuPA Open Proteomics 11, 23-27, 2016 | 52 | 2016 |
| Distinguishing Loss of Structure from Subunit Dissociation for Protein Complexes with Variable Temperature Ion Mobility Mass Spectrometry KJ Pacholarz, PE Barran Analytical chemistry 87 (12), 6271-6279, 2015 | 51 | 2015 |
| Insights into the Conformations of Three Structurally Diverse Proteins: Cytochrome c, p53, and MDM2, Provided by Variable-Temperature Ion Mobility Mass … ER Dickinson, E Jurneczko, KJ Pacholarz, DJ Clarke, M Reeves, KL Ball, ... Analytical chemistry 87 (6), 3231-3238, 2015 | 45 | 2015 |
| Structure-functional changes in eNAMPT at high concentrations mediate mouse and human beta cell dysfunction in type 2 diabetes SR Sayers, RL Beavil, NHF Fine, GC Huang, P Choudhary, KJ Pacholarz, ... Diabetologia 63, 313-323, 2020 | 39 | 2020 |
| Molecular Insights into the Thermal Stability of mAbs with Variable‐Temperature Ion‐Mobility Mass Spectrometry KJ Pacholarz, SJ Peters, RA Garlish, AJ Henry, RJ Taylor, DP Humphreys, ... ChemBioChem 17 (1), 46-51, 2016 | 35 | 2016 |
| Hybrid mass spectrometry methods reveal lot-to-lot differences and delineate the effects of glycosylation on the tertiary structure of Herceptin® R Upton, LG Migas, KJ Pacholarz, RG Beniston, S Estdale, D Firth, ... Chemical science 10 (9), 2811-2820, 2019 | 34 | 2019 |
| Hybrid mass spectrometry approaches to determine how L-histidine feedback regulates the enzyzme MtATP-phosphoribosyltransferase KJ Pacholarz, RJ Burnley, TA Jowitt, V Ordsmith, JP Pisco, M Porrini, ... Structure 25 (5), 730-738. e4, 2017 | 26 | 2017 |
| Charge mediated compaction and rearrangement of gas-phase proteins: a case study considering two proteins at opposing ends of the structure-disorder continuum JR Jhingree, B Bellina, KJ Pacholarz, PE Barran Journal of The American Society for Mass Spectrometry 28 (7), 1450-1461, 2017 | 25 | 2017 |
| Uncoupling conformational states from activity in an allosteric enzyme JP Pisco, C De Chiara, KJ Pacholarz, A Garza-Garcia, RW Ogrodowicz, ... Nature communications 8 (1), 203, 2017 | 23 | 2017 |
| MhuD from Mycobacterium tuberculosis: Probing a Dual Role in Heme Storage and Degradation SJ Matthews, KJ Pacholarz, AP France, TA Jowitt, S Hay, PE Barran, ... ACS infectious diseases 5 (11), 1855-1866, 2019 | 15 | 2019 |
| Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches LN Jeffreys, KJ Pacholarz, LO Johannissen, HM Girvan, PE Barran, ... Journal of Biological Chemistry 295 (22), 7595-7607, 2020 | 12 | 2020 |
| Reference protocol to assess analytical performance of higher order structural analysis measurements: results from an interlaboratory comparison K Groves, AE Ashcroft, A Cryar, A Sula, BA Wallace, BB Stocks, C Burns, ... Analytical Chemistry 93 (26), 9041-9048, 2021 | 4 | 2021 |
| Biochemical characterisation of class III biotin protein ligases from Botrytis cinerea and Zymoseptoria tritici LM Sternicki, S Nguyen, KJ Pacholarz, P Barran, NR Pendini, GW Booker, ... Archives of Biochemistry and Biophysics 691, 108509, 2020 | 3 | 2020 |
| Investigation of large protein and multimeric protein complex structures with mass spectrometry techniques KJ Pacholarz The University of Edinburgh, 2015 | 1 | 2015 |
| Activation of L-histidine biosynthesis as a new antibiotic strategy against Mycobacterium tuberculosis LP de Carvalho, D Hunt, J Pisco, A Rodgers, C de Chiara, A Zaveri, ... | | 2024 |
| The Application of Mass Spectrometry for the Characterization of Monoclonal Antibody‐Based Therapeutics R Upton, KJ Pacholarz, D Firth, S Estdale, PE Barran Analysis of Protein Post‐Translational Modifications by Mass Spectrometry …, 2016 | | 2016 |
| EXAMINING THE M/Z SEPARATIVE CAPABILITY OF TRAVELLING WAVES FOR LARGE MOLECULE CHARACTERISATION J Ujma, D Langridge, K Richardson, K Pacholarz, E Liggett, J Wildgoose, ... | | |
Perdita BarranProfessor Mass Spectrometry University of ManchesterVerified email at manchester.ac.uk
