Monther Abu-Remaileh
Monther Abu-Remaileh
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An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis
K Birsoy, T Wang, WW Chen, E Freinkman, M Abu-Remaileh, DM Sabatini
Cell 162 (3), 540-551, 2015
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ...
Nature 531 (7592), 53-58, 2016
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
S Epsztejn-Litman, N Feldman, M Abu-Remaileh, Y Shufaro, A Gerson, ...
Nature structural & molecular biology 15 (11), 1176-1183, 2008
Lysosomal metabolomics reveals V-ATPase-and mTOR-dependent regulation of amino acid efflux from lysosomes
M Abu-Remaileh, GA Wyant, C Kim, NN Laqtom, M Abbasi, SH Chan, ...
Science 358 (6364), 807-813, 2017
Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase
JR Cantor, M Abu-Remaileh, N Kanarek, E Freinkman, X Gao, ...
Cell 169 (2), 258-272. e17, 2017
A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate
ME Pacold, KR Brimacombe, SH Chan, JM Rohde, CA Lewis, ...
Nature chemical biology 12 (6), 452-458, 2016
mTORC1 activator SLC38A9 is required to efflux essential amino acids from lysosomes and use protein as a nutrient
GA Wyant, M Abu-Remaileh, RL Wolfson, WW Chen, E Freinkman, ...
Cell 171 (3), 642-654. e12, 2017
Fasting activates fatty acid oxidation to enhance intestinal stem cell function during homeostasis and aging
MM Mihaylova, CW Cheng, AQ Cao, S Tripathi, MD Mana, ...
Cell stem cell 22 (5), 769-778. e4, 2018
NUFIP1 is a ribosome receptor for starvation-induced ribophagy
GA Wyant, M Abu-Remaileh, EM Frenkel, NN Laqtom, V Dharamdasani, ...
Science 360 (6390), 751-758, 2018
KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1
RL Wolfson, L Chantranupong, GA Wyant, X Gu, JM Orozco, K Shen, ...
Nature 543 (7645), 438-442, 2017
Histidine catabolism is a major determinant of methotrexate sensitivity
N Kanarek, HR Keys, JR Cantor, CA Lewis, SH Chan, T Kunchok, ...
Nature 559 (7715), 632-636, 2018
Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation
RA Weber, FS Yen, SPV Nicholson, H Alwaseem, EC Bayraktar, M Alam, ...
Molecular cell 77 (3), 645-655. e7, 2020
Structural basis for the docking of mTORC1 on the lysosomal surface
KB Rogala, X Gu, JF Kedir, M Abu-Remaileh, LF Bianchi, AMS Bottino, ...
Science 366 (6464), 468-475, 2019
The microbiota programs DNA methylation to control intestinal homeostasis and inflammation
I Ansari, G Raddatz, J Gutekunst, M Ridnik, D Cohen, M Abu-Remaileh, ...
Nature microbiology 5 (4), 610-619, 2020
Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer
M Abu-Remaileh, S Bender, G Raddatz, I Ansari, D Cohen, J Gutekunst, ...
Cancer research 75 (10), 2120-2130, 2015
R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response
MP Crossley, C Song, MJ Bocek, JH Choi, JN Kousouros, ...
Nature 613 (7942), 187-194, 2023
MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo
EC Bayraktar, L Baudrier, C Özerdem, CA Lewis, SH Chan, T Kunchok, ...
Proceedings of the National Academy of Sciences 116 (1), 303-312, 2019
Oct‐3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β‐catenin signalling
M Abu‐Remaileh, A Gerson, M Farago, G Nathan, I Alkalay, ...
The EMBO journal 29 (19), 3236-3248, 2010
Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation
M Abu-Remaileh, RI Aqeilan
Cell Death & Differentiation 21 (11), 1805-1814, 2014
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
GC Forcina, L Pope, M Murray, W Dong, M Abu-Remaileh, CR Bertozzi, ...
Proceedings of the National Academy of Sciences 119 (11), e2118646119, 2022
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