| An essential role of the mitochondrial electron transport chain in cell proliferation is to enable aspartate synthesis K Birsoy, T Wang, WW Chen, E Freinkman, M Abu-Remaileh, DM Sabatini Cell 162 (3), 540-551, 2015 | 1312 | 2015 |
| High-fat diet enhances stemness and tumorigenicity of intestinal progenitors S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ... Nature 531 (7592), 53-58, 2016 | 778 | 2016 |
| Lysosomal metabolomics reveals V-ATPase-and mTOR-dependent regulation of amino acid efflux from lysosomes M Abu-Remaileh, GA Wyant, C Kim, NN Laqtom, M Abbasi, SH Chan, ... Science 358 (6364), 807-813, 2017 | 561 | 2017 |
| De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes S Epsztejn-Litman, N Feldman, M Abu-Remaileh, Y Shufaro, A Gerson, ... Nature structural & molecular biology 15 (11), 1176-1183, 2008 | 534 | 2008 |
| Physiologic medium rewires cellular metabolism and reveals uric acid as an endogenous inhibitor of UMP synthase JR Cantor, M Abu-Remaileh, N Kanarek, E Freinkman, X Gao, ... Cell 169 (2), 258-272. e17, 2017 | 513 | 2017 |
| A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate ME Pacold, KR Brimacombe, SH Chan, JM Rohde, CA Lewis, ... Nature chemical biology 12 (6), 452-458, 2016 | 489 | 2016 |
| mTORC1 activator SLC38A9 is required to efflux essential amino acids from lysosomes and use protein as a nutrient GA Wyant, M Abu-Remaileh, RL Wolfson, WW Chen, E Freinkman, ... Cell 171 (3), 642-654. e12, 2017 | 442 | 2017 |
| Fasting activates fatty acid oxidation to enhance intestinal stem cell function during homeostasis and aging MM Mihaylova, CW Cheng, AQ Cao, S Tripathi, MD Mana, ... Cell stem cell 22 (5), 769-778. e4, 2018 | 371 | 2018 |
| NUFIP1 is a ribosome receptor for starvation-induced ribophagy GA Wyant, M Abu-Remaileh, EM Frenkel, NN Laqtom, V Dharamdasani, ... Science 360 (6390), 751-758, 2018 | 329 | 2018 |
| KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1 RL Wolfson, L Chantranupong, GA Wyant, X Gu, JM Orozco, K Shen, ... Nature 543 (7645), 438-442, 2017 | 317 | 2017 |
| Histidine catabolism is a major determinant of methotrexate sensitivity N Kanarek, HR Keys, JR Cantor, CA Lewis, SH Chan, T Kunchok, ... Nature 559 (7715), 632-636, 2018 | 292 | 2018 |
| Maintaining iron homeostasis is the key role of lysosomal acidity for cell proliferation RA Weber, FS Yen, SPV Nicholson, H Alwaseem, EC Bayraktar, M Alam, ... Molecular cell 77 (3), 645-655. e7, 2020 | 185 | 2020 |
| Structural basis for the docking of mTORC1 on the lysosomal surface KB Rogala, X Gu, JF Kedir, M Abu-Remaileh, LF Bianchi, AMS Bottino, ... Science 366 (6464), 468-475, 2019 | 158 | 2019 |
| The microbiota programs DNA methylation to control intestinal homeostasis and inflammation I Ansari, G Raddatz, J Gutekunst, M Ridnik, D Cohen, M Abu-Remaileh, ... Nature microbiology 5 (4), 610-619, 2020 | 136 | 2020 |
| R-loop-derived cytoplasmic RNA–DNA hybrids activate an immune response MP Crossley, C Song, MJ Bocek, JH Choi, JN Kousouros, ... Nature 613 (7942), 187-194, 2023 | 122 | 2023 |
| Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer M Abu-Remaileh, S Bender, G Raddatz, I Ansari, D Cohen, J Gutekunst, ... Cancer research 75 (10), 2120-2130, 2015 | 109 | 2015 |
| MITO-Tag Mice enable rapid isolation and multimodal profiling of mitochondria from specific cell types in vivo EC Bayraktar, L Baudrier, C Özerdem, CA Lewis, SH Chan, T Kunchok, ... Proceedings of the National Academy of Sciences 116 (1), 303-312, 2019 | 94 | 2019 |
| Oct‐3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β‐catenin signalling M Abu‐Remaileh, A Gerson, M Farago, G Nathan, I Alkalay, ... The EMBO journal 29 (19), 3236-3248, 2010 | 87 | 2010 |
| Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation M Abu-Remaileh, RI Aqeilan Cell Death & Differentiation 21 (11), 1805-1814, 2014 | 77 | 2014 |
| Ferroptosis regulation by the NGLY1/NFE2L1 pathway GC Forcina, L Pope, M Murray, W Dong, M Abu-Remaileh, CR Bertozzi, ... Proceedings of the National Academy of Sciences 119 (11), e2118646119, 2022 | 66 | 2022 |
David M. SabatiniInstitute of Organic Chemistry and Biochemistry of the CASVerified email at uochb.cas.cz
