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Heinrich Kovar
Heinrich Kovar
Unknown affiliation
Verified email at ccri.at
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Cited by
Year
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours
O Delattre, J Zucman, B Plougastel, C Desmaze, T Melot, M Peter, ...
Nature 359 (6391), 162-165, 1992
21121992
MIC2 is a specific marker for Ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of Ewing's sarcoma and peripheral primitive …
IM Ambros, PF Ambros, S Strehl, H Kovar, H Gadner, M Salzer‐Kuntschik
Cancer 67 (7), 1886-1893, 1991
7731991
Ewing sarcoma: current management and future approaches through collaboration
N Gaspar, DS Hawkins, U Dirksen, IJ Lewis, S Ferrari, MC Le Deley, ...
Journal of Clinical Oncology 33 (27), 3036-3046, 2015
7112015
Ewing sarcoma
TGP Grünewald, F Cidre-Aranaz, D Surdez, EM Tomazou, E de Álava, ...
Nature reviews Disease primers 4 (1), 5, 2018
6952018
Ewing's sarcoma family of tumors: current management
M Bernstein, H Kovar, M Paulussen, RL Randall, A Schuck, LA Teot, ...
The oncologist 11 (5), 503-519, 2006
6452006
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation
GHS Richter, S Plehm, A Fasan, S Rössler, R Unland, IM Bennani-Baiti, ...
Proceedings of the National Academy of Sciences 106 (13), 5324-5329, 2009
3582009
Does expression of different EWS chimeric transcripts define clinically distinct risk groups of Ewing tumor patients?
A Zoubek, B Dockhorn-Dworniczak, O Delattre, H Christiansen, F Niggli, ...
Journal of clinical oncology 14 (4), 1245-1251, 1996
3461996
Impact of EWS-ETS Fusion Type on Disease Progression in Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor: Prospective Results From the …
MC Le Deley, O Delattre, KL Schaefer, SA Burchill, G Koehler, ...
Journal of Clinical Oncology 28 (12), 1982-1988, 2010
2552010
Overexpression of the pseudoautosomal gene MIC2 in Ewing's sarcoma and peripheral primitive neuroectodermal tumor.
H Kovar, M Dworzak, S Strehl, E Schnell, IM Ambros, PF Ambros, ...
Oncogene 5 (7), 1067-1070, 1990
2341990
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma
NC Sheffield, G Pierron, J Klughammer, P Datlinger, A Schönegger, ...
Nature medicine 23 (3), 386-395, 2017
2292017
Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1
EM Tomazou, NC Sheffield, C Schmidl, M Schuster, A Schönegger, ...
Cell reports 10 (7), 1082-1095, 2015
2232015
A molecular function map of Ewing's sarcoma
M Kauer, J Ban, R Kofler, B Walker, S Davis, P Meltzer, H Kovar
PloS one 4 (4), e5415, 2009
2132009
EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro
H Kovar, DNT Aryee, G Jug, C Henockl, M Schemper, O Delattre, ...
Cell Growth and Differentiation-Publication American Association for Cancer …, 1996
2071996
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma
S Postel-Vinay, AS Véron, F Tirode, G Pierron, S Reynaud, H Kovar, ...
Nature genetics 44 (3), 323-327, 2012
2062012
EWS-FLI1 and EWS-ERG Gene Fusions Are Associated With Similar Clinical Phenotypes in Ewing's Sarcoma
JP Ginsberg, E de Alava, M Ladanyi, LH Wexler, H Kovar, M Paulussen, ...
Journal of Clinical Oncology 17 (6), 1809-1809, 1999
2011999
Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II
R Petermann, BM Mossier, DNT Aryee, V Khazak, EA Golemis, H Kovar
Oncogene 17 (5), 603-610, 1998
1851998
Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells
OM Tirado, S Mateo-Lozano, J Villar, LE Dettin, A Llort, S Gallego, J Ban, ...
Cancer research 66 (20), 9937-9947, 2006
1812006
Ewing sarcoma—diagnosis, treatment, clinical challenges and future perspectives
SK Zöllner, JF Amatruda, S Bauer, S Collaud, E de Álava, SG DuBois, ...
Journal of clinical medicine 10 (8), 1685, 2021
1772021
Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors
H Kovar, G Jug, DNT Aryee, A Zoubek, P Ambros, B Gruber, R Windhager, ...
Oncogene 15 (18), 2225-2232, 1997
1721997
Dr. Jekyll and Mr. Hyde: the two faces of the FUS/EWS/TAF15 protein family
H Kovar
Sarcoma 2011 (1), 837474, 2011
1512011
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