Leila Williams
Leila Williams
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Loss of PTEN promotes resistance to T cell–mediated immunotherapy
W Peng, JQ Chen, C Liu, S Malu, C Creasy, MT Tetzlaff, C Xu, ...
Cancer discovery 6 (2), 202-216, 2016
Increased tumor glycolysis characterizes immune resistance to adoptive T cell therapy
T Cascone, JA McKenzie, RM Mbofung, S Punt, Z Wang, C Xu, ...
Cell metabolism 27 (5), 977-987. e4, 2018
RNA editing derived epitopes function as cancer antigens to elicit immune responses
M Zhang, J Fritsche, J Roszik, LJ Williams, X Peng, Y Chiu, CC Tsou, ...
Nature communications 9 (1), 3919, 2018
HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes
RM Mbofung, JA McKenzie, S Malu, M Zhang, W Peng, C Liu, I Kuiatse, ...
Nature communications 8 (1), 451, 2017
The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A expression
L Huang, S Malu, JA McKenzie, MC Andrews, AH Talukder, T Tieu, ...
Clinical Cancer Research 24 (14), 3366-3376, 2018
The effect of topoisomerase I inhibitors on the efficacy of T-cell-based cancer immunotherapy
JA McKenzie, RM Mbofung, S Malu, M Zhang, E Ashkin, S Devi, ...
JNCI: Journal of the National Cancer Institute 110 (7), 777-786, 2018
The glutaminase inhibitor CB-839 (telaglenastat) enhances the antimelanoma activity of T-cell–mediated immunotherapies
S Varghese, S Pramanik, LJ Williams, HR Hodges, CW Hudgens, ...
Molecular cancer therapeutics 20 (3), 500-511, 2021
Superior efficacy of neoadjuvant compared to adjuvant immune checkpoint blockade in non-small cell lung cancer
T Cascone, H Hamdi, F Zhang, A Poteete, L Li, CW Hudgens, LJ Williams, ...
Cancer Research 78 (13_Supplement), 1719-1719, 2018
Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma
W Peng, LJ Williams, C Xu, B Melendez, JA McKenzie, Y Chen, ...
Clinical Cancer Research 25 (21), 6406-6416, 2019
Integrating genome-wide CRISPR immune screen with multi-omic clinical data reveals distinct classes of tumor intrinsic immune regulators
J Hou, Y Wang, L Shi, Y Chen, C Xu, A Saeedi, K Pan, R Bohat, NA Egan, ...
Journal for immunotherapy of cancer 9 (2), 2021
Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity
S Punt, S Malu, JA McKenzie, SZ Manrique, EM Doorduijn, RM Mbofung, ...
Cancer Immunology, Immunotherapy 70, 1101-1113, 2021
LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade
A Hickman, J Koetsier, T Kurtanich, MC Nielsen, G Winn, Y Wang, ...
The Journal of clinical investigation 132 (13), 2022
Inhibiting Type I Arginine Methyltransferase Activity Promotes T Cell–Mediated Antitumor Immune Responses
A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, ...
Cancer Immunology Research 10 (4), 420-436, 2022
Loss of PTEN promotes resistance to T cell-mediated immunotherapy. Cancer Discov. 2016; 6 (2): 202–16
W Peng, JQ Chen, C Liu, S Malu, C Creasy, MT Tetzlaff
External Resources Crossref (DOI), 0
Loss of PTEN promotes resistance to T cell-mediated immunotherapy. Cancer Discov. 2016; 6: 202–16
W Peng, JQ Chen, C Liu, S Malu, C Creasy, MT Tetzlaff, C Xu, ...
Weiyi Peng
C Liu, L Williams, C Xu, RM Mbofung
Abstracts: AACR Virtual Special Conference: Endometrial Cancer: New Biology …, 2020
Complex speech-language therapy interventions for stroke-related aphasia: the RELEASE study incorporating a systematic review and individual participant data network meta-analysis
MC Brady, M Ali, KV Berg, LJ Williams, LR Williams, M Abo, F Becker, ...
Health and Social Care Delivery Research 10 (28), 2022
Early Drug Prescription Patterns as Predictors of Final Workers Compensation Claim Costs and Closure: An Updated Analysis on an Expanded Cohort
XG Tao, RA Lavin, L Yuspeh, NF Tsourmas, N Kalia, N Leung, L Williams, ...
Journal of occupational and environmental medicine 64 (12), 1046-1052, 2022
186 Development of KSQ-001, an engineered TIL (eTIL) therapy for solid tumors through CRISPR/Cas9-mediated editing of SOCS1
K Wong, S Lin, C Wrocklage, K Sofjan, L Williams, M Brady, N Colletti, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A198-A198, 2021
204 KSQ-004: Unbiased pair-wise discovery of SOCS1 and Regnase-1 as the top CRISPR/Cas9 dual-edit combination enhancing in vivo TIL potency against solid tumors
K Wong, C Wrocklage, S Lin, I Le Mercier, C Bullock, L Cadzow, ...
J Immunother 9 (2), A1-A1054, 2021
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