Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling C Gewinner, ZC Wang, A Richardson, J Teruya-Feldstein, ... Cancer cell 16 (2), 115-125, 2009 | 514 | 2009 |
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5 C Gewinner, G Hart, N Zachara, R Cole, C Beisenherz-Huss, B Groner Journal of Biological Chemistry 279 (5), 3563-3572, 2004 | 217 | 2004 |
PI3K/AKT/mTOR pathway in ovarian cancer treatment: are we on the right track? ML Gasparri, E Bardhi, I Ruscito, A Papadia, AA Farooqi, C Marchetti, ... Geburtshilfe und Frauenheilkunde 77 (10), 1095-1103, 2017 | 142 | 2017 |
Characterization of Enterocoliticin, a Phage Tail-Like Bacteriocin, and Its Effect on Pathogenic Yersinia enterocolitica Strains E Strauch, H Kaspar, C Schaudinn, P Dersch, K Madela, C Gewinner, ... Applied and environmental microbiology 67 (12), 5634-5642, 2001 | 128 | 2001 |
An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth LC Young, N Hartig, M Muñoz-Alegre, JA Oses-Prieto, S Durdu, S Bender, ... Molecular cell 52 (5), 679-692, 2013 | 111 | 2013 |
EGF-receptor specificity for phosphotyrosine-primed substrates provides signal integration with Src MJ Begley, C Yun, CA Gewinner, JM Asara, JL Johnson, AJ Coyle, ... Nature structural & molecular biology 22 (12), 983-990, 2015 | 48 | 2015 |
Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment LRH Ip, G Poulogiannis, FC Viciano, J Sasaki, S Kofuji, VJ Spanswick, ... Oncotarget 6 (12), 10548, 2015 | 32 | 2015 |
Tyrosine kinase BMX phosphorylates phosphotyrosine-primed motif mediating the activation of multiple receptor tyrosine kinases S Chen, X Jiang, CA Gewinner, JM Asara, NI Simon, C Cai, LC Cantley, ... Science signaling 6 (277), ra40-ra40, 2013 | 27 | 2013 |
Characterization of plasmid regions of foodborne Yersinia enterocolitica biogroup 1A strains hybridizing to the Yersinia enterocolitica virulence plasmid B Hoffmann, E Strauch, C Gewinner, H Nattermann, B Appel Systematic and applied microbiology 21 (2), 201-211, 1998 | 23 | 1998 |
Identification of kinases and phosphatases that regulate ATG4B activity by siRNA and small molecule screening in cells N Pengo, K Prak, JR Costa, C Luft, A Agrotis, J Freeman, CA Gewinner, ... Frontiers in Cell and Developmental Biology 6, 148, 2018 | 22 | 2018 |
Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype GO Alli-Balogun, CA Gewinner, R Jacobs, J Kriston-Vizi, MG Waugh, ... Molecular biology of the cell 27 (25), 4033-4042, 2016 | 19 | 2016 |
Autophagy gene expression profiling identifies a defective microtubule-associated protein light chain 3A mutant in cancer JR Costa, K Prak, S Aldous, CA Gewinner, R Ketteler Oncotarget 7 (27), 41203, 2016 | 18 | 2016 |
Functional assessment of glucocerebrosidase modulator efficacy in primary patient-derived macrophages is essential for drug development and patient stratification NJ Welsh, CA Gewinner, K Mistry, M Koglin, J Cooke, M Butler, B Powney, ... haematologica 105 (5), e206, 2020 | 7 | 2020 |
Antagonism of inhibitors of apoptosis proteins reveals a novel, immune response-based therapeutic approach for T-cell lymphoma N Ferrari, G Ward, C Gewinner, MP Davis, S Jueliger, H Saini, J Munck, ... Blood Advances 5 (20), 4003-4016, 2021 | 6 | 2021 |
ASTX660, a non-peptidomimetic antagonist of cIAP1/2 and XIAP, enhances immune mediated tumor killing and induction of immunogenic cell death N Ferrari, G Ward, J Munck, S Jueliger, M Davis, C Gewinner, ... Cancer Research 80 (16_Supplement), 5542-5542, 2020 | 1 | 2020 |
X-Ray Crystal Structure of STAT Proteins and Structure-Activity Relationships CW Müller, M Soler-Lopez, C Gewinner, B Groner Signal Transducers and Activators of Transcription (STATs) Activation and …, 2003 | 1 | 2003 |
Identifikation und Charakterisierung der dynamischen O-GlcNAc-Modifikation von Stat5a C Gewinner Frankfurt (Main), Univ., Diss., 2002, 2001 | 1 | 2001 |
Identification of biomarkers of response to MDM2 inhibition in solid tumours using computational, multi-omics approaches H Saini, M Davis, JL Ferraldeschi, N Wallis, N Thompson Thorax 71, 380-382, 2024 | | 2024 |
SOS1 inhibition in combination with HER2 inhibition in models of HER2-driven cancer RL Schenk, K Kostyrko, J Popow, C Gewinner, A Baum, C Albrecht, ... Cancer Research 84 (6_Supplement), 6506-6506, 2024 | | 2024 |
Antagonism of inhibitors of apoptosis proteins reveals a novel, immune response-based therapeutic approach for T-cell lymphoma (vol 5, pg 4003, 2021) N Ferrari, G Ward, C Gewinner BLOOD ADVANCES 6 (8), 2548-2548, 2022 | | 2022 |