Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature methods 16 (7), 595-602, 2019 | 605 | 2019 |
HIV-1 neutralizing antibodies induced by native-like envelope trimers RW Sanders, MJ van Gils, R Derking, D Sok, TJ Ketas, JA Burger, ... Science 349 (6244), aac4223, 2015 | 561 | 2015 |
Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2 AC Walls, B Fiala, A Schäfer, S Wrenn, MN Pham, M Murphy, ... Cell 183 (5), 1367-1382. e17, 2020 | 499 | 2020 |
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env Y Do Kwon, M Pancera, P Acharya, IS Georgiev, ET Crooks, J Gorman, ... Nature structural & molecular biology 22 (7), 522-531, 2015 | 389 | 2015 |
Immunogenicity of stabilized HIV-1 envelope trimers with reduced exposure of non-neutralizing epitopes SW De Taeye, G Ozorowski, AT de la Peņa, M Guttman, JP Julien, ... Cell 163 (7), 1702-1715, 2015 | 357 | 2015 |
Quadrivalent influenza nanoparticle vaccines induce broad protection S Boyoglu-Barnum, D Ellis, RA Gillespie, GB Hutchinson, YJ Park, ... Nature 592 (7855), 623-628, 2021 | 245 | 2021 |
Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design J Gorman, C Soto, MM Yang, TM Davenport, M Guttman, RT Bailer, ... Nature structural & molecular biology 23 (1), 81-90, 2016 | 196 | 2016 |
Advances in hydrogen/deuterium exchange mass spectrometry and the pursuit of challenging biological systems EI James, TA Murphree, C Vorauer, JR Engen, M Guttman Chemical reviews 122 (8), 7562-7623, 2021 | 184 | 2021 |
Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra M Guttman, DD Weis, JR Engen, KK Lee Journal of the American Society for Mass Spectrometry 24 (12), 1906-1912, 2013 | 181 | 2013 |
Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env M Guttman, A Cupo, JP Julien, RW Sanders, IA Wilson, JP Moore, KK Lee Nature communications 6 (1), 6144, 2015 | 169 | 2015 |
Sequential and simultaneous immunization of rabbits with HIV-1 envelope glycoprotein SOSIP. 664 trimers from clades A, B and C PJ Klasse, CC LaBranche, TJ Ketas, G Ozorowski, A Cupo, P Pugach, ... PLoS pathogens 12 (9), e1005864, 2016 | 160 | 2016 |
Improving the immunogenicity of native-like HIV-1 envelope trimers by hyperstabilization AT de la Pena, JP Julien, SW de Taeye, F Garces, M Guttman, ... Cell reports 20 (8), 1805-1817, 2017 | 158 | 2017 |
An unexpected twist in viral capsid maturation I Gertsman, L Gan, M Guttman, K Lee, JA Speir, RL Duda, RW Hendrix, ... Nature 458 (7238), 646-650, 2009 | 155 | 2009 |
CD4-induced activation in a soluble HIV-1 Env trimer M Guttman, NK Garcia, A Cupo, T Matsui, JP Julien, RW Sanders, ... Structure 22 (7), 974-984, 2014 | 146 | 2014 |
Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV MG Joyce, B Zhang, L Ou, M Chen, GY Chuang, A Druz, WP Kong, YT Lai, ... Nature structural & molecular biology 23 (9), 811-820, 2016 | 137 | 2016 |
Local and global structural drivers for the photoactivation of the orange carotenoid protein S Gupta, M Guttman, RL Leverenz, K Zhumadilova, EG Pawlowski, ... Proceedings of the National Academy of Sciences 112 (41), E5567-E5574, 2015 | 136 | 2015 |
Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers RP Ringe, A Yasmeen, G Ozorowski, EP Go, LK Pritchard, M Guttman, ... Journal of virology 89 (23), 12189-12210, 2015 | 107 | 2015 |
Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120 M Guttman, M Kahn, NK Garcia, SL Hu, KK Lee Journal of virology 86 (16), 8750-8764, 2012 | 85 | 2012 |
Dynamic changes during acid-induced activation of influenza hemagglutinin NK Garcia, M Guttman, JL Ebner, KK Lee Structure 23 (4), 665-676, 2015 | 84 | 2015 |
Site-specific mapping of sialic acid linkage isomers by ion mobility spectrometry M Guttman, KK Lee Analytical chemistry 88 (10), 5212-5217, 2016 | 83 | 2016 |