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Bismuth antimicrobial drugs serve as broad-spectrum metallo-β-lactamase inhibitors
R Wang, TP Lai, P Gao, H Zhang, PL Ho, PCY Woo, G Ma, RYT Kao, H Li, ...
Nature communications 9 (1), 439, 2018
2172018
HKOCl-3: a fluorescent hypochlorous acid probe for live-cell and in vivo imaging and quantitative application in flow cytometry and a 96-well microplate assay
JJ Hu, NK Wong, MY Lu, X Chen, S Ye, AQ Zhao, P Gao, RYT Kao, ...
Chemical science 7 (3), 2094-2099, 2016
1452016
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance
H Wang, M Wang, X Xu, P Gao, Z Xu, Q Zhang, H Li, A Yan, RYT Kao, ...
Nature communications 12 (1), 3331, 2021
1112021
Suppression of Staphylococcus aureus virulence by a small-molecule compound
P Gao, PL Ho, B Yan, KH Sze, J Davies, RYT Kao
Proceedings of the National Academy of Sciences 115 (31), 8003-8008, 2018
542018
Dehydrosqualene Desaturase as a Novel Target for Anti-Virulence Therapy against Staphylococcus aureus
P Gao, J Davies, RYT Kao
MBio 8 (5), 10.1128/mbio. 01224-17, 2017
502017
Natural products triptolide, celastrol, and withaferin A inhibit the chaperone activity of peroxiredoxin I
Q Zhao, Y Ding, Z Deng, OY Lee, P Gao, P Chen, RJ Rose, H Zhao, ...
Chemical science 6 (7), 4124-4130, 2015
502015
A discovery of novel Mycobacterium tuberculosis pantothenate synthetase inhibitors based on the molecular mechanism of actinomycin D inhibition
Y Yang, P Gao, Y Liu, X Ji, M Gan, Y Guan, X Hao, Z Li, C Xiao
Bioorganic & medicinal chemistry letters 21 (13), 3943-3946, 2011
402011
Methylation of daptomycin leading to the discovery of kynomycin, a cyclic lipodepsipeptide active against resistant pathogens
HY Chow, KHL Po, P Gao, P Blasco, X Wang, C Li, L Ye, K Jin, K Chen, ...
Journal of Medicinal Chemistry 63 (6), 3161-3171, 2020
302020
Identification and validation of a novel lead compound targeting 4-diphosphocytidyl-2-C-methylerythritol synthetase (IspD) of mycobacteria
P Gao, Y Yang, C Xiao, Y Liu, M Gan, Y Guan, X Hao, J Meng, S Zhou, ...
European journal of pharmacology 694 (1-3), 45-52, 2012
292012
A tailored positively-charged hydrophobic surface reduces the risk of implant associated infections
J Shen, P Gao, S Han, RYT Kao, S Wu, X Liu, S Qian, PK Chu, ...
Acta Biomaterialia 114, 421-430, 2020
262020
Adenosine synthase A contributes to recurrent Staphylococcus aureus infection by dampening protective immunity
J Deng, B Zhang, H Chu, X Wang, Y Wang, HR Gong, R Li, D Yang, C Li, ...
EBioMedicine 70, 2021
162021
Construction of a Multiplex Promoter Reporter Platform to Monitor Staphylococcus aureus Virulence Gene Expression and the Identification of Usnic Acid as a Potent …
P Gao, Y Wang, I Villanueva, PL Ho, J Davies, RYT Kao
Frontiers in microbiology 7, 1344, 2016
132016
Broad and effective protection against Staphylococcus aureus is elicited by a multivalent vaccine formulated with novel antigens
J Deng, X Wang, BZ Zhang, P Gao, Q Lin, RYT Kao, K Gustafsson, ...
Msphere 4 (5), 10.1128/msphere. 00362-19, 2019
92019
Isolation, purification, identification of structure and study of bioactivity of anti-TB active component 9005B
Z Zhang, P Gao, Y Guan, CL Xiao, XQ Hao
Chinese Journal of Antibiotics, 2009
92009
Subinhibitory concentrations of antibiotics exacerbate staphylococcal infection by inducing bacterial virulence
P Gao, Y Wei, RE Wan, KW Wong, HTV Iu, SSC Tai, Y Li, HCB Yam, ...
Microbiology Spectrum 10 (4), e00640-22, 2022
72022
Digging Deeper to Save the Old Anti-Tuberculosis Target: D-Alanine–D-Alanine Ligase with a Novel Inhibitor, IMB-0283
J Meng, P GAO, X Wang, Y Guan, Y Liu, C Xiao
Frontiers in Microbiology 10, 3017, 2020
72020
Screening repurposed antiviral small molecules as antimycobacterial compounds by a lux-based phoP promoter-reporter platform
L Zhu, AWT Lee, KKL Wu, P Gao, KKG Tam, R Rajwani, GC Chaburte, ...
Antibiotics 11 (3), 369, 2022
52022
Linoleic acid metabolism activation in macrophages promotes the clearing of intracellular Staphylococcus aureus
B Yan, K Fung, S Ye, PM Lai, YX Wei, KH Sze, D Yang, P Gao, RY Kao
Chemical Science 13, 12445-12460, 2022
42022
A cell-based screening system for detection of inhibitors toward mycobacterial cell wall core
P Gao, Y Guan, D Song, C Xiao
The Journal of Antibiotics 62 (6), 315-318, 2009
32009
SaeR as a novel target for antivirulence therapy against Staphylococcus aureus
P Gao, Y Wei, S Hou, PM Lai, H Liu, SSC Tai, VYM Tang, PH Prakash, ...
Emerging Microbes & Infections 12 (2), 2254415, 2023
22023
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