Transcriptional architecture of the primate neocortex A Bernard, LS Lubbers, KQ Tanis, R Luo, AA Podtelezhnikov, EM Finney, ... Neuron 73 (6), 1083-1099, 2012 | 250 | 2012 |
Two distinct phosphorylation pathways have additive effects on Abl family kinase activation KQ Tanis, D Veach, HS Duewel, WG Bornmann, AJ Koleske Molecular and cellular biology, 2003 | 199 | 2003 |
Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure CJ Winrow, KQ Tanis, DR Reiss, AM Rigby, JM Uslaner, VN Uebele, ... Neuropharmacology 58 (1), 185-194, 2010 | 128 | 2010 |
Comparative transcriptomics of choroid plexus in Alzheimer’s disease, frontotemporal dementia and Huntington’s disease: implications for CSF homeostasis EG Stopa, KQ Tanis, MC Miller, EV Nikonova, AA Podtelezhnikov, ... Fluids and Barriers of the CNS 15, 1-10, 2018 | 100 | 2018 |
Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging AA Podtelezhnikov, KQ Tanis, M Nebozhyn, WJ Ray, DJ Stone, ... PloS one 6 (12), e29610, 2011 | 96 | 2011 |
Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation ES Arnardottir, EV Nikonova, KR Shockley, AA Podtelezhnikov, RC Anafi, ... Sleep 37 (10), 1589-1600, 2014 | 86 | 2014 |
CREB binding and activity in brain: regional specificity and induction by electroconvulsive seizure KQ Tanis, RS Duman, SS Newton Biological psychiatry 63 (7), 710-720, 2008 | 82 | 2008 |
Intracellular signaling pathways pave roads to recovery for mood disorders KQ Tanis, RS Duman Annals of medicine 39 (7), 531-544, 2007 | 74 | 2007 |
Targeting neurotrophic/growth factor expression and signaling for antidepressant drug development KQ Tanis, SS Newton, RS Duman CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2007 | 70 | 2007 |
The transcriptomic signature of disease development and progression of nonalcoholic fatty liver disease S Cazanave, A Podtelezhnikov, K Jensen, M Seneshaw, DP Kumar, ... Scientific reports 7 (1), 17193, 2017 | 66 | 2017 |
Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease PE Cramer, RC Gentzel, KQ Tanis, J Vardigan, Y Wang, B Connolly, ... Neurobiology of aging 64, 92-106, 2018 | 49 | 2018 |
Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms X Cao, KQ Tanis, AJ Koleske, J Colicelli Journal of Biological Chemistry 283 (46), 31401-31407, 2008 | 49 | 2008 |
Human Alzheimer’s disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology SM Rothman, KQ Tanis, P Gandhi, V Malkov, J Marcus, M Pearson, ... Journal of neuroinflammation 15, 1-15, 2018 | 47 | 2018 |
Transcriptional responses to loss or gain of function of the leucine-rich repeat kinase 2 (LRRK2) gene uncover biological processes modulated by LRRK2 activity EV Nikonova, Y Xiong, KQ Tanis, VL Dawson, RL Vogel, EM Finney, ... Human molecular genetics 21 (1), 163-174, 2012 | 46 | 2012 |
Application of a rat liver drug bioactivation transcriptional response assay early in drug development that informs chemically reactive metabolite formation and potential for … JJ Monroe, KQ Tanis, AA Podtelezhnikov, T Nguyen, SV Machotka, ... Toxicological Sciences 177 (1), 281-299, 2020 | 32 | 2020 |
Analysis of target genes regulated by chronic electroconvulsive therapy reveals role for Fzd6 in depression B Voleti, KQ Tanis, SS Newton, RS Duman Biological psychiatry 71 (1), 51-58, 2012 | 30 | 2012 |
Quantitative transcriptional biomarkers of xenobiotic receptor activation in rat liver for the early assessment of drug safety liabilities AA Podtelezhnikov, JJ Monroe, AG Aslamkhan, K Pearson, C Qin, ... Toxicological Sciences 175 (1), 98-112, 2020 | 28 | 2020 |
Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in … W Kang, AA Podtelezhnikov, KQ Tanis, S Pacchione, M Su, KB Bleicher, ... Toxicological Sciences 177 (1), 121-139, 2020 | 26 | 2020 |
Toxicogenomics in drug development: a match made in heaven? C Qin, KQ Tanis, AA Podtelezhnikov, WE Glaab, FD Sistare, JJ DeGeorge Expert Opinion on Drug Metabolism & Toxicology 12 (8), 847-849, 2016 | 25 | 2016 |
Induction of Alzheimer’s‐like changes in brain of mice expressing mutant APP fed excess methionine A McCampbell, K Wessner, MW Marlatt, C Wolffe, D Toolan, ... Journal of neurochemistry 116 (1), 82-92, 2011 | 24 | 2011 |