Derek Macmillan
Derek Macmillan
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Evolving strategies for enzyme engineering
JD Bloom, MM Meyer, P Meinhold, CR Otey, D MacMillan, FH Arnold
Current opinion in structural biology 15 (4), 447-452, 2005
The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus
SM Currie, EG Findlay, BJ McHugh, A Mackellar, T Man, D Macmillan, ...
PloS one 8 (8), e73659, 2013
Selective in vitro glycosylation of recombinant proteins: semi-synthesis of novel homogeneous glycoforms of human erythropoietin
D Macmillan, RM Bill, KA Sage, D Fern, SL Flitsch
Chemistry & biology 8 (2), 133-145, 2001
Evolving strategies for protein synthesis converge on native chemical ligation
D Macmillan
Angewandte Chemie International Edition 45 (46), 7668-7672, 2006
Modular assembly of glycoproteins: towards the synthesis of GlyCAM‐1 by using expressed protein ligation
D Macmillan, CR Bertozzi
Angewandte Chemie International Edition 43 (11), 1355-1359, 2004
Rapid synthesis of acyl transfer auxiliaries for cysteine-free native glycopeptide ligation
D Macmillan, DW Anderson
Organic Letters 6 (25), 4659-4662, 2004
Analysis and separation of residues important for the chemoattractant and antimicrobial activities of β-defensin 3
K Taylor, DJ Clarke, B McCullough, W Chin, E Seo, D Yang, J Oppenheim, ...
Journal of Biological Chemistry 283 (11), 6631-6639, 2008
Design and synthesis of a homogeneous erythropoietin analogue with two human complex‐type sialyloligosaccharides: combined use of chemical and bacterial protein expression methods
K Hirano, D Macmillan, K Tezuka, T Tsuji, Y Kajihara
Angewandte Chemie International Edition 48 (50), 9557-9560, 2009
Peptide and protein thioester synthesis via N→ S acyl transfer
J Kang, D Macmillan
Organic & Biomolecular Chemistry 8 (9), 1993-2002, 2010
Development of an ion mobility quadrupole time of flight mass spectrometer
BJ McCullough, J Kalapothakis, H Eastwood, P Kemper, D MacMillan, ...
Analytical chemistry 80 (16), 6336-6344, 2008
Solid-phase synthesis of thioether-linked glycopeptide mimics for application to glycoprotein semisynthesis
D Macmillan, AM Daines, M Bayrhuber, SL Flitsch
Organic Letters 4 (9), 1467-1470, 2002
New directions in glycoprotein engineering
D Macmillan, CR Bertozzi
Tetrahedron 56 (48), 9515-9525, 2000
3-Mercaptopropionic acid-mediated synthesis of peptide and protein thioesters
J Kang, JP Richardson, D Macmillan
Chemical communications, 407-409, 2009
Small-molecule inhibition of c-MYC: MAX leucine zipper formation is revealed by ion mobility mass spectrometry
SR Harvey, M Porrini, C Stachl, D MacMillan, G Zinzalla, PE Barran
Journal of the American Chemical Society 134 (47), 19384-19392, 2012
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
S Jungmichel, JA Clapperton, J Lloyd, FJ Hari, C Spycher, L Pavic, J Li, ...
Nucleic acids research 40 (9), 3913-3928, 2012
Cysteine promoted C‐terminal hydrazinolysis of native peptides and proteins
AL Adams, B Cowper, RE Morgan, B Premdjee, S Caddick, D Macmillan
Angewandte Chemie 125 (49), 13300-13304, 2013
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity
Y Zhu, J Underwood, D Macmillan, L Shariff, R O'Shaughnessy, JI Harper, ...
Journal of Allergy and Clinical Immunology 140 (5), 1310-1322. e5, 2017
Peptide thioester synthesis through N→ S acyl-transfer: application to the synthesis of a β-defensin
J Kang, NL Reynolds, C Tyrrell, JR Dorin, D Macmillan
Organic & Biomolecular Chemistry 7 (23), 4918-4923, 2009
[General Articles] Recent Developments in the Synthesis and Discovery of Oligosaccharides and Glycoconjugates for the Treatment of Disease
D Macmillan, AM Daines
Current medicinal chemistry 10 (24), 2733-2773, 2003
Exploring neoglycoprotein assembly through native chemical ligation using neoglycopeptide thioesters prepared via N→ S acyl transfer
JP Richardson, CH Chan, J Blanc, M Saadi, D Macmillan
Organic & Biomolecular Chemistry 8 (6), 1351-1360, 2010
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