Bertrand AIGLE
Bertrand AIGLE
UniversitÚ de Lorraine, UMR UL-INRA 1128
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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
M Wang, JJ Carver, VV Phelan, LM Sanchez, N Garg, Y Peng, ...
Nature biotechnology 34 (8), 828-837, 2016
Minimum information about a biosynthetic gene cluster
MH Medema, R Kottmann, P Yilmaz, M Cummings, JB Biggins, K Blin, ...
Nature chemical biology 11 (9), 625-631, 2015
Towards the sustainable discovery and development of new antibiotics
M Miethke, M Pieroni, T Weber, M Br÷nstrup, P Hammann, L Halby, ...
Nature Reviews Chemistry 5 (10), 726-749, 2021
Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens
L Laureti, L Song, S Huang, C Corre, P Leblond, GL Challis, B Aigle
Proceedings of the National Academy of Sciences 108 (15), 6258-6263, 2011
Evolution of the Terminal Regions of the Streptomyces Linear Chromosome
F Choulet, B Aigle, A Gallois, S Mangenot, C Gerbaud, C Truong, ...
Molecular Biology and Evolution 23 (12), 2361-2369, 2006
Genome mining of Streptomyces ambofaciens
B Aigle, S Lautru, D Spiteller, JS Dickschat, GL Challis, P Leblond, ...
Journal of Industrial Microbiology and Biotechnology 41 (2), 251-263, 2014
Characterization and Manipulation of the Pathway-Specific Late Regulator AlpW Reveals Streptomyces ambofaciens as a New Producer of Kinamycins
R Bunet, L Song, MV Mendes, C Corre, L Hotel, N Rouhier, X Framboisier, ...
Journal of Bacteriology 193 (5), 1142-1153, 2011
Functional Angucycline-Like Antibiotic Gene Cluster in the Terminal Inverted Repeats of the Streptomyces ambofaciens Linear Chromosome
X Pang, B Aigle, JM Girardet, S Mangenot, JL Pernodet, B Decaris, ...
Antimicrobial agents and chemotherapy 48 (2), 575-588, 2004
Pseudomonas fluorescens pirates both ferrioxamine and ferricoelichelin siderophores from Streptomyces ambofaciens
J Galet, A Deveau, L H˘tel, P Frey-Klett, P Leblond, B Aigle
Applied and Environmental Microbiology 81 (9), 3132-3141, 2015
Involvement of AlpV, a New Member of the Streptomyces Antibiotic Regulatory Protein Family, in Regulation of the Duplicated Type II Polyketide Synthase alp Gene Cluster iná…
B Aigle, X Pang, B Decaris, P Leblond
Journal of bacteriology 187 (7), 2491-2500, 2005
Waking up Streptomyces secondary metabolism by constitutive expression of activators or genetic disruption of repressors
B Aigle, C Corre
Methods in enzymology 517, 343-366, 2012
A single amino acid substitution in region 1.2 of the principal σ factor of Streptomyces coelicolor A3 (2) results in pleiotropic loss of antibiotic production
B Aigle, A Wietzorrek, E Takano, MJ Bibb
Molecular microbiology 37 (5), 995-1004, 2002
Role of secondary metabolites in the interaction between Pseudomonas fluorescens and soil microorganisms under iron-limited conditions
A Deveau, H Gross, B Palin, S Mehnaz, M Schnepf, P Leblond, ...
FEMS Microbiology Ecology 92 (8), fiw107, 2016
A single Sfp-type phosphopantetheinyl transferase plays a major role in the biosynthesis of PKS and NRPS derived metabolites in Streptomyces ambofaciens ATCC23877
R Bunet, R Riclea, L Laureti, L Hotel, C Paris, JM Girardet, D Spiteller, ...
PLoS One 9 (1), e87607, 2014
Regulation of the Synthesis of the Angucyclinone Antibiotic Alpomycin in Streptomyces ambofaciens by the Autoregulator Receptor AlpZ and Its Specific Ligand
R Bunet, MV Mendes, N Rouhier, X Pang, L Hotel, P Leblond, B Aigle
Journal of bacteriology 190 (9), 3293-3305, 2008
Comparative Genomics among Closely Related Streptomyces Strains Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity
CM Vicente, A Thibessard, JN Lorenzi, M Benhadj, L H˘tel, ...
Antibiotics 7 (4), 86, 2018
End‐to‐end fusion of linear deleted chromosomes initiates a cycle of genome instability in Streptomyces ambofaciens
T Wenner, V Roth, G Fischer, C Fourrier, B Aigle, B Decaris, P Leblond
Molecular microbiology 50 (2), 411-425, 2003
Identification of Alp1U and Lom6 as epoxy hydrolases and implications for kinamycin and lomaiviticin biosynthesis
B Wang, F Guo, J Ren, G Ai, B Aigle, K Fan, K Yang
Nature Communications 6 (1), 7674, 2015
Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the spiramycin producer
A Thibessard, D Haas, C Gerbaud, B Aigle, S Lautru, JL Pernodet, ...
Journal of Biotechnology 214, 117-118, 2015
Expression of the Streptomyces coelicolor A3 (2) ptpA gene encoding a phosphotyrosine protein phosphatase leads to overproduction of secondary metabolites in S. lividans
T Umeyama, Y Tanabe, BD Aigle, S Horinouchi
FEMS microbiology letters 144 (2‐3), 177-184, 2006
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